سعر باكليتاكسفيل 30 مجم/5 مل 2022

Paclitaxel 30 mg/5 ml (6 mg/ml) concentrate for intravenous infusion, imported from Filaxis Laboratories (Argentina) via Multipharma; cytotoxic taxane chemotherapy.

• Advanced ovarian carcinoma (first-line with cisplatin, and subsequent therapy)Population: AdultsDailyMed (U.S. National Library of Medicine)
• Breast cancer: adjuvant node-positive (after doxorubicin-containing therapy) and metastatic after failure of combination chemotherapyPopulation: AdultsDailyMed (U.S. National Library of Medicine)
• Non-small cell lung cancer, first-line with cisplatinPopulation: AdultsDailyMed (U.S. National Library of Medicine)

• History of hypersensitivity to paclitaxel or other drugs formulated in polyoxyl 35 castor oil.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Baseline neutrophil count below 1,500 cells/mm3 in solid tumours, or below 1,000 cells/mm3 in AIDS-related Kaposi sarcoma.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warning: administer under supervision of a physician experienced in cancer chemotherapy; anaphylaxis and severe hypersensitivity (2-4%, some fatal) - premedicate all patients with corticosteroids, diphenhydramine and H2 antagonists; do not rechallenge after severe reactions.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Bone marrow suppression (mainly neutropenia) is dose-dependent and dose-limiting; neutrophil nadir at a median of 11 days.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• CisplatinGive paclitaxel before cisplatin; cisplatin first lowers paclitaxel clearance by about 20% and increases myelosuppression.DailyMed (U.S. National Library of Medicine)

• Can cause fetal harm when given to a pregnant woman; avoid pregnancy during treatment.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Paclitaxel: Antimicrotubule agent that promotes microtubule assembly by enhancing tubulin polymerisation, forming stable non-functional microtubules and disrupting the dynamic equilibrium of the microtubule system needed for mitosis.