سعر بريجافالكس 25 مجم 2022

Pregavalex 25 mg oral capsules containing pregabalin, marketed in Egypt by EVA Pharma; pack of 30 capsules.

• Neuropathic pain associated with diabetic peripheral neuropathyPopulation: AdultsDailyMed (U.S. National Library of Medicine)
• Postherpetic neuralgiaPopulation: AdultsDailyMed (U.S. National Library of Medicine)
• Adjunctive therapy for partial-onset seizuresPopulation: Patients 1 month of age and olderDailyMed (U.S. National Library of Medicine)

• Most common in adults: dizziness, somnolence, dry mouth, edema, blurred vision, weight gain, thinking abnormal (US label).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to pregabalin or any of its components (US label).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Angioedema and hypersensitivity reactions can occur; discontinue immediately (US label).International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Antiepileptic drugs including pregabalin increase the risk of suicidal thoughts or behavior (US label).International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Taper gradually over at least 1 week; abrupt discontinuation may increase seizure risk and cause withdrawal symptoms (US label).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Opioids and other CNS depressantsConcomitant use may cause respiratory depression; additive CNS depressant effects (US label).DailyMed (U.S. National Library of Medicine)

• US label: observational studies suggest a possible small increase in overall major birth defects without a consistent pattern; pregnancy registry available.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• US label: breastfeeding is not recommended during pregabalin treatment.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Pregabalin: Binds with high affinity to the alpha2-delta auxiliary subunit of voltage-gated calcium channels in CNS tissue; does not bind GABA-A/GABA-B or benzodiazepine receptors (US label).