سعر كيبولم 25مجم 20 قرص 2025

Quetiapine 25 mg film-coated tablets, pack of 20; atypical antipsychotic (Medisave Developed (manufactured by Medizen Pharmaceutical Industries)).

• Schizophrenia (adults and adolescents 13-17 years)Population: Adults; adolescents 13-17 yearsDailyMed (NLM)
• Bipolar I disorder: acute manic episodes, as monotherapy or adjunct to lithium or divalproexPopulation: Adults; children/adolescents 10-17 years (monotherapy)DailyMed (NLM)
• Bipolar disorder: acute depressive episodes (monotherapy)Population: AdultsDailyMed (NLM)

• Serious adverse reactions discussed in the label include cerebrovascular events in elderly dementia patients, neuroleptic malignant syndrome, metabolic changes (hyperglycaemia, dyslipidaemia, weight gain), tardive dyskinesia, hypotension, falls and blood pressure increases in children and adolescents.International label, same formulation · DailyMed (NLM)

• Known hypersensitivity to quetiapine or to any excipient of the formulation (anaphylactic reactions have been reported).International label, same formulation · DailyMed (NLM)

• Boxed warning: increased mortality in elderly patients with dementia-related psychosis treated with antipsychotics; quetiapine is not approved for dementia-related psychosis.International label, same formulation · DailyMed (NLM)
• Boxed warning: antidepressants increased the risk of suicidal thoughts and behaviours in children, adolescents and young adults in short-term studies; monitor closely for clinical worsening and emergence of suicidal thoughts.International label, same formulation · DailyMed (NLM)

• Strong CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)Reduce the quetiapine dose to one sixth when co-administered.DailyMed (NLM)
• Strong CYP3A4 inducers (e.g., phenytoin, rifampin, St John's wort)Increase quetiapine dose up to 5-fold with chronic (>7-14 days) inducer treatment; reduce by 5-fold within 7-14 days after the inducer is stopped.DailyMed (NLM)
• Alcohol and other centrally acting drugsQuetiapine potentiated the cognitive and motor effects of alcohol; use caution with other CNS-active drugs and limit alcohol.DailyMed (NLM)

• Published epidemiologic data have not established a drug-associated risk of major birth defects, miscarriage or adverse maternal or fetal outcomes; untreated psychiatric illness carries maternal risk. A pregnancy exposure registry for atypical antipsychotics exists.International label, same formulation · DailyMed (NLM)
• Limited published data show quetiapine in human milk at a relative infant dose below 1% of the maternal weight-adjusted dose, with no consistent adverse effects reported in breastfed infants; weigh benefits against risks.International label, same formulation · DailyMed (NLM)