سعر ريفاستينج10ملجرام/5مل شراب120مل 2022

Rivastig 10 mg/5 ml syrup

معلومات الدواء

دواعي الاستعمالUses

Symptomatic treatment of mild to moderately severe Alzheimer's dementiaالفئة: AdultsEuropean Medicines Agency
Symptomatic treatment of mild to moderately severe dementia in patients with idiopathic Parkinson's diseaseالفئة: AdultsEuropean Medicines Agency

Symptomatic treatment of mild to moderately severe Alzheimer's dementiaPopulation: AdultsEuropean Medicines Agency
Symptomatic treatment of mild to moderately severe dementia in patients with idiopathic Parkinson's diseasePopulation: AdultsEuropean Medicines Agency

الآثار الجانبيةSide effects

Most commonly reported adverse reactions are gastrointestinal, including nausea (38%) and vomiting (23%), especially during titration; women are more susceptible to GI reactions and weight loss.نشرة دولية لنفس التركيبة · European Medicines Agency

Most commonly reported adverse reactions are gastrointestinal, including nausea (38%) and vomiting (23%), especially during titration; women are more susceptible to GI reactions and weight loss.International label, same formulation · European Medicines Agency

موانع الاستعمالContraindications

Hypersensitivity to rivastigmine, other carbamate derivatives or any excipient.نشرة دولية لنفس التركيبة · European Medicines Agency
Previous history of application-site reactions suggestive of allergic contact dermatitis with rivastigmine patch.نشرة دولية لنفس التركيبة · European Medicines Agency

Hypersensitivity to rivastigmine, other carbamate derivatives or any excipient.International label, same formulation · European Medicines Agency
Previous history of application-site reactions suggestive of allergic contact dermatitis with rivastigmine patch.International label, same formulation · European Medicines Agency

تحذيرات واحتياطاتWarnings & precautions

QT prolongation and bradycardia (a risk factor for torsade de pointes) may occur; caution in patients with QTc prolongation risk, sick sinus syndrome or conduction defects; ECG monitoring may be required.نشرة دولية لنفس التركيبة · European Medicines Agency
Caution in active gastric or duodenal ulcers, asthma or obstructive pulmonary disease, urinary obstruction and seizure predisposition; monitor body weight during therapy.نشرة دولية لنفس التركيبة · European Medicines Agency

QT prolongation and bradycardia (a risk factor for torsade de pointes) may occur; caution in patients with QTc prolongation risk, sick sinus syndrome or conduction defects; ECG monitoring may be required.International label, same formulation · European Medicines Agency
Caution in active gastric or duodenal ulcers, asthma or obstructive pulmonary disease, urinary obstruction and seizure predisposition; monitor body weight during therapy.International label, same formulation · European Medicines Agency

التداخلات الدوائيةDrug interactions

QT-prolonging or bradycardic agents (e.g. class III antiarrhythmics, calcium channel antagonists, digitalis, some antipsychotics)Use with caution and clinical (ECG) monitoring because bradycardia is a risk factor for torsades de pointes.European Medicines Agency

QT-prolonging or bradycardic agents (e.g. class III antiarrhythmics, calcium channel antagonists, digitalis, some antipsychotics)Use with caution and clinical (ECG) monitoring because bradycardia is a risk factor for torsades de pointes.European Medicines Agency

الحمل والرضاعةPregnancy & breastfeeding

No clinical data on exposed pregnancies; should not be used during pregnancy unless clearly necessary.نشرة دولية لنفس التركيبة · European Medicines Agency
Rivastigmine is excreted in animal milk; women on rivastigmine should not breast-feed.نشرة دولية لنفس التركيبة · European Medicines Agency

No clinical data on exposed pregnancies; should not be used during pregnancy unless clearly necessary.International label, same formulation · European Medicines Agency
Rivastigmine is excreted in animal milk; women on rivastigmine should not breast-feed.International label, same formulation · European Medicines Agency

كيف يعمل الدواءHow it works

Reversible cholinesterase inhibitor; thought to enhance cholinergic function by increasing acetylcholine concentration through inhibition of its hydrolysis (US label 12.1).

Rivastigmine: Reversible cholinesterase inhibitor; thought to enhance cholinergic function by increasing acetylcholine concentration through inhibition of its hydrolysis (US label 12.1).

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