سعر رومالكس 100مجم 5 اقماع لبوس 2024

Diclofenac sodium 100 mg rectal suppositories, pack of 5, by Alexandria Company for Pharmaceuticals (Egypt).

• Adults: relief of pain and inflammation in rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, acute gout, acute musculoskeletal disorders (periarthritis, tendinitis, tenosynovitis, bursitis) and painful conditions from trauma, fractures, low back pain, sprains, strains, dislocations, orthopaedic, dental and minor surgery.electronic medicines compendium (emc)

• Common: headache, dizziness, vertigo, nausea, vomiting, diarrhoea, dyspepsia, abdominal pain, flatulence, anorexia, raised transaminases, rash.International label, same formulation · electronic medicines compendium (emc)
• Rare/very rare: GI haemorrhage or ulcer with perforation, hepatitis, hypersensitivity/anaphylaxis, asthma, blood dyscrasias, severe skin reactions, acute renal failure; uncommon (long-term high dose): myocardial infarction, cardiac failure.International label, same formulation · electronic medicines compendium (emc)

• Hypersensitivity to diclofenac or any excipient; active gastric or intestinal ulcer, bleeding or perforation; history of NSAID-related GI bleeding or perforation; active or recurrent peptic ulcer/haemorrhage; last trimester of pregnancy; hepatic failure; renal failure; established congestive heart failure (NYHA II-IV), ischaemic heart disease, peripheral arterial disease and/or cerebrovascular disease; asthma, angioedema, urticaria or acute rhinitis precipitated by ibuprofen, aspirin or other NSAIDs.International label, same formulation · electronic medicines compendium (emc)
• Proctitis (suppositories).International label, same formulation · electronic medicines compendium (emc)

• Use the lowest effective dose for the shortest duration; avoid combination with other systemic NSAIDs including COX-2 inhibitors.International label, same formulation · electronic medicines compendium (emc)
• Gastrointestinal bleeding, ulceration or perforation, which can be fatal, may occur at any time; consider gastroprotection (misoprostol or PPI) in high-risk patients and stop treatment if GI bleeding occurs.International label, same formulation · electronic medicines compendium (emc)
• Increased risk of arterial thrombotic events (myocardial infarction, stroke), particularly at 150 mg/day and with long-term use; treat patients with cardiovascular risk factors only after careful consideration.International label, same formulation · electronic medicines compendium (emc)

• LithiumDiclofenac may increase plasma lithium; monitor serum lithium.electronic medicines compendium (emc)
• DigoxinDiclofenac may raise plasma digoxin; monitor serum digoxin.electronic medicines compendium (emc)
• Diuretics and antihypertensives (ACE inhibitors, beta-blockers)Reduced antihypertensive effect and increased nephrotoxicity risk; monitor blood pressure and renal function, keep patients hydrated.electronic medicines compendium (emc)

• Diclofenac passes into breast milk in small amounts; should not be administered during breast-feeding.International label, same formulation · electronic medicines compendium (emc)

• Diclofenac sodium: Inhibits prostaglandin synthetase (cyclo-oxygenase).