سعر سابوفين 100مجم 5 لبوس شرجي 2022

Suppofen diclofenac sodium 100 mg rectal suppositories (5 suppositories), Marcyrl / El-Obour (Egypt); NSAID (acetic acid derivative) for pain and inflammation.

• Relief of pain and inflammation in arthritic conditions (rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, acute gout), acute musculoskeletal disorders and painful conditions from trauma, fracture, low back pain, sprains and minor surgeryPopulation: Adults and elderlyelectronic medicines compendium (eMC)

• Common: headache, dizziness, vertigo, nausea, vomiting, diarrhoea, dyspepsia, abdominal pain, flatulence, anorexia. Rare/very rare: GI haemorrhage, hypersensitivity/anaphylaxis, blood dyscrasias, hepatitis, renal and skin reactions; myocardial infarction and cardiac failure (uncommon).International label, same formulation · electronic medicines compendium (eMC)

• Hypersensitivity to diclofenac or excipients; asthma, angioedema, urticaria or rhinitis precipitated by ibuprofen, aspirin or other NSAIDs.International label, same formulation · electronic medicines compendium (eMC)
• Active gastric or intestinal ulcer, bleeding or perforation; history of NSAID-related GI bleeding/perforation or recurrent peptic ulcer/haemorrhage.International label, same formulation · electronic medicines compendium (eMC)
• Established congestive heart failure (NYHA II-IV), ischaemic heart disease, peripheral arterial disease or cerebrovascular disease.International label, same formulation · electronic medicines compendium (eMC)

• GI bleeding, ulceration or perforation, which can be fatal, may occur at any time; withdraw if it occurs. Caution with corticosteroids, anticoagulants, SSRIs or antiplatelets and in ulcerative colitis or Crohn's disease.International label, same formulation · electronic medicines compendium (eMC)
• Cardiovascular risk may increase with dose and duration; use the lowest effective dose for the shortest time.International label, same formulation · electronic medicines compendium (eMC)
• Liver enzymes may rise; monitor hepatic function during prolonged treatment and stop if abnormalities persist. Caution in hepatic porphyria.International label, same formulation · electronic medicines compendium (eMC)

• Corticosteroids, anticoagulants (e.g. warfarin), SSRIs, antiplatelets (e.g. aspirin)Increased risk of GI ulceration or bleeding; use with caution.electronic medicines compendium (eMC)

• Diclofenac passes into breast milk in small amounts; should not be given during breastfeeding.International label, same formulation · electronic medicines compendium (eMC)

• Diclofenac sodium: Inhibits cyclo-oxygenase (COX-1 and COX-2), reducing prostaglandin synthesis and thereby pain, inflammation and fever.