سعر روباتوكلير 10 مجم أقراص 2024

Rupatadine 10 mg oral tablets (Horus for Pharmaceutical Products, Egypt), a second-generation H1 antihistamine; pack size listed inconsistently (10 or 20 tablets).

• Symptomatic treatment of allergic rhinitis and urticaria in adults and adolescents over 12 years.Population: Adults and adolescents over 12 yearselectronic medicines compendium (emc), UK

• Common in trials: somnolence (9.4%), headache (6.9%), fatigue (3.1%), asthenia (1.5%), dry mouth (1.2%), dizziness (1.03%).International label, equivalent formulation · electronic medicines compendium (emc), UK

• Hypersensitivity to rupatadine or to any of the excipients.International label, equivalent formulation · electronic medicines compendium (emc), UK

• Grapefruit juice is not recommended with rupatadine.International label, equivalent formulation · electronic medicines compendium (emc), UK
• Use with caution in known QT prolongation, uncorrected hypokalaemia, or ongoing proarrhythmic conditions (e.g. clinically significant bradycardia, acute myocardial ischaemia).International label, equivalent formulation · electronic medicines compendium (emc), UK
• The UK tablets contain lactose; not for patients with rare hereditary galactose intolerance, total lactase deficiency or glucose-galactose malabsorption.General active-ingredient information · electronic medicines compendium (emc), UK

• Potent CYP3A4 inhibitors (e.g. itraconazole, ketoconazole, voriconazole, posaconazole, HIV protease inhibitors, clarithromycin, nefazodone)Avoid co-administration; they increase rupatadine exposure.electronic medicines compendium (emc), UK
• Moderate CYP3A4 inhibitors (erythromycin, fluconazole, diltiazem)Use with caution.electronic medicines compendium (emc), UK
• Sensitive or narrow-therapeutic-index CYP3A4 substrates (e.g. simvastatin, lovastatin, ciclosporin, tacrolimus, sirolimus, everolimus, cisapride)Dose adjustment may be required because rupatadine may increase their plasma concentrations.electronic medicines compendium (emc), UK

• Limited data in pregnancy; as a precaution, avoid use during pregnancy.International label, equivalent formulation · electronic medicines compendium (emc), UK
• A decision to continue or stop breastfeeding or therapy should weigh the benefit of breastfeeding for the child against the benefit of therapy for the mother.International label, equivalent formulation · electronic medicines compendium (emc), UK

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