سعر هيلثتادين 10 مجم 10 أقراص 2022

Rupatadine 10 mg tablets (Pharmed Healthcare), 10 tablets.

• Symptomatic treatment of allergic rhinitis and urticaria in adults and adolescents over 12 years.Population: Adults and adolescents over 12 yearselectronic medicines compendium (emc), UK

• Most common in trials: somnolence (9.4%), headache (6.9%), fatigue (3.1%), asthenia, dry mouth and dizziness. Rare post-marketing: tachycardia, palpitations, hypersensitivity including anaphylaxis and angioedema.International label, same formulation · electronic medicines compendium (emc), UK

• Hypersensitivity to rupatadine or any excipient.International label, same formulation · electronic medicines compendium (emc), UK

• Avoid grapefruit juice and potent CYP3A4 inhibitors; use moderate CYP3A4 inhibitors with caution. Dose adjustment of sensitive or narrow-therapeutic-index CYP3A4 substrates may be required.International label, same formulation · electronic medicines compendium (emc), UK
• Use with caution with known QT prolongation, uncorrected hypokalaemia or proarrhythmic conditions; the UK tablet contains lactose.International label, same formulation · electronic medicines compendium (emc), UK

• Potent CYP3A4 inhibitors (ketoconazole, itraconazole, voriconazole, posaconazole, HIV protease inhibitors, clarithromycin)Avoid: ketoconazole increased rupatadine exposure about 10-fold.electronic medicines compendium (emc), UK
• Moderate CYP3A4 inhibitors (erythromycin, fluconazole, diltiazem)Use with caution: erythromycin increased exposure 2-3-fold.electronic medicines compendium (emc), UK
• Grapefruit juiceIncreased rupatadine exposure 3.5-fold; do not take together.electronic medicines compendium (emc), UK

• Limited data in pregnant women; animal studies show no harmful effects. As a precaution, preferably avoid use during pregnancy.International label, same formulation · electronic medicines compendium (emc), UK
• Excreted in animal milk; unknown in human milk. Decide whether to discontinue breastfeeding or the therapy.International label, same formulation · electronic medicines compendium (emc), UK

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