سعر سارتاليس 300مجم 14 اقراص 2022

Sartaless 300 mg scored tablets (irbesartan), pack of 14, by Sigma (Egypt); an angiotensin II receptor blocker.

• Treatment of hypertension, to lower blood pressure.Population: Adults with hypertensionDailyMed (U.S. National Library of Medicine)
• Diabetic nephropathy in patients with type 2 diabetes and hypertension, elevated serum creatinine and proteinuria (>300 mg/day).Population: Adults with type 2 diabetes, hypertension and nephropathyDailyMed (U.S. National Library of Medicine)

• Hypertension trials (vs placebo): diarrhoea (3% vs 2%), dyspepsia/heartburn (2% vs 1%) and fatigue (4% vs 3%); not associated with increased dry cough.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Hypersensitivity to any component of the product.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Do not coadminister aliskiren in patients with diabetes.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warning - fetal toxicity: drugs acting on the renin-angiotensin system can cause injury and death to the developing fetus; discontinue as soon as pregnancy is detected.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Symptomatic hypotension may occur after initiation in volume- or salt-depleted patients; correct depletion first or use a lower starting dose.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Changes in renal function including acute renal failure may occur, particularly in renal artery stenosis, chronic kidney disease, severe heart failure or volume depletion.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Agents increasing serum potassiumCoadministration may cause hyperkalaemia, sometimes severe; monitor serum potassium.DailyMed (U.S. National Library of Medicine)
• LithiumIncreased serum lithium and lithium toxicity reported; monitor lithium levels.DailyMed (U.S. National Library of Medicine)
• NSAIDs including selective COX-2 inhibitorsMay deteriorate renal function (possible acute renal failure) in elderly, volume-depleted or renally impaired patients and may attenuate the antihypertensive effect; monitor renal function.DailyMed (U.S. National Library of Medicine)

• Can cause fetal harm; RAS-acting drugs in the second and third trimesters reduce fetal renal function and increase fetal and neonatal morbidity and death (oligohydramnios, lung hypoplasia, skull hypoplasia, anuria, renal failure). Discontinue as soon as pregnancy is detected.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• No human milk data; present in rat milk; breastfeeding is not recommended.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Irbesartan: Selectively blocks the binding of angiotensin II to the AT1 receptor, inhibiting its vasoconstrictor and aldosterone-secreting effects.