سعر Seretide Evohaler 50/25 mcg 2026

• Regular treatment of asthma where a combination of long-acting beta2-agonist and inhaled corticosteroid is appropriate (patients not adequately controlled on inhaled corticosteroid plus as-needed short-acting beta2-agonist, or already controlled on both).Population: Adults, adolescents and children 4 years and olderelectronic medicines compendium (emc), UK

• Very common: headache and nasopharyngitis. Common: oral and throat candidiasis, pneumonia (in COPD), hoarseness/dysphonia, hypokalaemia and muscle cramps, among others listed in the SmPC.International label, same formulation · electronic medicines compendium (emc), UK

• Hypersensitivity to the active substances or to any of the excipients.International label, same formulation · electronic medicines compendium (emc), UK
• Primary treatment of status asthmaticus or other acute episodes of asthma requiring intensive measures; hypersensitivity to any ingredient.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Not for relief of acute asthma symptoms (a rapid-acting reliever should be available); should not be started during an exacerbation or significantly worsening asthma, and should not be stopped abruptly.International label, same formulation · electronic medicines compendium (emc), UK
• Use with caution in patients with severe cardiovascular disorders or heart rhythm abnormalities, diabetes mellitus, thyrotoxicosis, uncorrected hypokalaemia, and active or quiescent pulmonary tuberculosis or other airway infections.International label, same formulation · electronic medicines compendium (emc), UK
• Systemic corticosteroid effects (adrenal suppression, growth retardation in children, decreased bone mineral density, cataract, glaucoma) may occur, particularly at high doses for prolonged periods; acute adrenal crisis has been described.International label, same formulation · electronic medicines compendium (emc), UK

• Beta-blockersBeta-blockers may weaken or antagonise the effect of salmeterol; avoid in asthma unless there are compelling reasons.electronic medicines compendium (emc), UK
• Ritonavir and other strong CYP3A4 inhibitorsRitonavir can greatly increase plasma fluticasone propionate concentrations (systemic corticosteroid effects); avoid unless the benefit outweighs the risk. Strong CYP3A4 inhibitors also increase salmeterol exposure.electronic medicines compendium (emc), UK
• Xanthine derivatives, steroids and diureticsPotentially serious hypokalaemia from beta2-agonist therapy may be potentiated by concomitant xanthine derivatives, steroids and diuretics.electronic medicines compendium (emc), UK

• More than 1000 pregnancy outcomes indicate no malformative or feto/neonatal toxicity related to Seretide; use only if the expected benefit to the mother outweighs any possible risk to the fetus, using the lowest effective fluticasone dose.International label, same formulation · electronic medicines compendium (emc), UK
• It is unknown whether salmeterol and fluticasone propionate are excreted in human milk; a risk to the breastfed infant cannot be excluded, so weigh breastfeeding against therapy.International label, same formulation · electronic medicines compendium (emc), UK

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