سعر سيروفلو 500/50مكجم باودر للاستنشاق 30 بليستر 2022

Seroflo 500/50 mcg is a Cipla (India) inhalation-powder product imported to Egypt, listed as 30 blister doses, each containing fluticasone 500 mcg and salmeterol 50 mcg (inhaled corticosteroid plus long-acting beta2 agonist) for regular maintenance treatment of obstructive airways disease.

• Regular treatment of asthma where a combination of a long-acting beta2 agonist and an inhaled corticosteroid is appropriatePopulation: Adults and adolescents 12 years and olderelectronic medicines compendium (emc), UK
• Symptomatic treatment of COPD with FEV1 <60% predicted and a history of repeated exacerbations despite regular bronchodilator therapy (50/500 strength)Population: Adultselectronic medicines compendium (emc), UK

• Very common: headache; common: oral/throat candidiasis, pneumonia (COPD), bronchitis, hypokalaemia; uncommon: hypersensitivity, anxiety, sleep disorders, tremor, palpitations; rare: Cushingoid features, adrenal suppression, oesophageal candidiasis.International label, equivalent formulation · electronic medicines compendium (emc), UK

• Hypersensitivity to the active substances or excipients.International label, equivalent formulation · electronic medicines compendium (emc), UK
• Primary treatment of status asthmaticus or other acute episodes requiring intensive measures; severe hypersensitivity to milk proteins (lactose-containing powder).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Not for acute symptoms; do not start during an exacerbation; serious asthma-related events may occur; paradoxical bronchospasm; systemic corticosteroid effects at high doses (adrenal suppression, reduced bone density, growth retardation in children, cataract/glaucoma); hypokalaemia; caution in cardiovascular disease; pneumonia risk in COPD.International label, equivalent formulation · electronic medicines compendium (emc), UK

• Ritonavir and other strong CYP3A4 inhibitors (e.g., ketoconazole)Marked increase in fluticasone and salmeterol exposure; Cushing syndrome/adrenal suppression reported; avoid unless benefit outweighs risk.electronic medicines compendium (emc), UK
• Beta-adrenergic blockersMay weaken or antagonise salmeterol; avoid in asthma unless compelling reasons.electronic medicines compendium (emc), UK

• More than 1000 pregnancy outcomes indicate no malformative or feto/neonatal toxicity; use only if expected benefit to the mother outweighs possible fetal risk, with the lowest effective fluticasone dose.International label, equivalent formulation · electronic medicines compendium (emc), UK
• Unknown whether salmeterol or fluticasone propionate pass into human milk (both excreted in rat milk); risk to breastfed infants cannot be excluded.International label, equivalent formulation · electronic medicines compendium (emc), UK

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