سعر مديكورفال 100مكجم/6مكجم 120 بخة 2024

Budesonide 100 mcg + formoterol fumarate dihydrate 6 mcg per metered actuation, 120 actuations, inhaler by MDI Pharma, Egypt; inhaled corticosteroid plus long-acting beta2-agonist for asthma/COPD maintenance.

• Common: oropharyngeal candida infection, pneumonia (in COPD), headache, tremor, palpitations, mild throat irritation, coughing and dysphonia including hoarseness.International label, equivalent formulation · electronic medicines compendium (emc), UK

• Hypersensitivity to budesonide, formoterol or any excipient.International label, equivalent formulation · electronic medicines compendium (emc), UK
• Primary treatment of status asthmaticus or other acute episodes of asthma or COPD requiring intensive measures.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Not for relief of acute bronchospasm; patients should keep a rescue inhaler available and not stop treatment without medical supervision. Sudden deterioration needs urgent assessment.International label, equivalent formulation · electronic medicines compendium (emc), UK
• Use with caution in thyrotoxicosis, phaeochromocytoma, diabetes, untreated hypokalaemia, severe cardiovascular disease or QTc prolongation; avoid potent CYP3A4 inhibitors (e.g. itraconazole, ritonavir).International label, equivalent formulation · electronic medicines compendium (emc), UK
• Systemic corticosteroid effects may occur at high doses for long periods (adrenal suppression, growth retardation in children, reduced bone density, cataract, glaucoma); pneumonia risk in COPD patients.International label, equivalent formulation · electronic medicines compendium (emc), UK

• Potent CYP3A4 inhibitors (itraconazole, ritonavir)Increase budesonide exposure; concomitant use should be avoided or the interval between doses kept as long as possible.electronic medicines compendium (emc), UK
• Xanthines, steroids, diureticsMay add to the hypokalaemic effect of beta2-agonists; monitor serum potassium.electronic medicines compendium (emc), UK

• No clinical data on exposed pregnancies for the combination; about 2000 exposed pregnancies show no increased teratogenic risk with inhaled budesonide; use only when benefits outweigh risks.International label, equivalent formulation · electronic medicines compendium (emc), UK
• Budesonide is excreted in breast milk without expected effects at therapeutic doses; formoterol transfer is unknown; use only if benefit to the mother outweighs risk to the child.International label, equivalent formulation · electronic medicines compendium (emc), UK

• Monitor serum potassium when high-dose beta2-agonist therapy is combined with xanthines, steroids or diuretics; consider additional blood glucose checks in diabetics; monitor HPA axis when transferring from oral steroids.International label, equivalent formulation · electronic medicines compendium (emc), UK

• Budesonide: Binds glucocorticoid receptors to suppress inflammatory gene expression in the airways.
• Formoterol fumarate dihydrate: Stimulates beta2-adrenoceptors, raising cyclic AMP and relaxing bronchial smooth muscle for about 12 hours.