سعر سيروبار 10مجم 10 اقراص 2022

Seropar 10 mg is an Egyptian (Alfacure Pharmaceuticals) oral tablet containing buspirone 10 mg, an azapirone anxiolytic, in packs of 10 tablets.

• Management of anxiety disorders or short-term relief of the symptoms of anxietyPopulation: AdultsDailyMed (U.S. National Library of Medicine)

• Hypersensitivity to buspirone; use with MAOIs intended to treat depression, or within 14 days of stopping either drug (serotonin syndrome and/or elevated blood pressure).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Grapefruit juice (large amounts)Double-strength grapefruit juice increased buspirone Cmax 4.3-fold and AUC 9.2-fold; avoid large amounts.DailyMed (U.S. National Library of Medicine)
• MAOIsContraindicated (serotonin syndrome, elevated blood pressure).DailyMed (U.S. National Library of Medicine)
• Strong CYP3A4 inhibitors (e.g., itraconazole) / CYP3A4 inducers (e.g., rifampin)Inhibitors markedly increase and inducers markedly decrease buspirone levels; adjust dose.DailyMed (U.S. National Library of Medicine)

• No fertility impairment or fetal damage in rat/rabbit studies at about 30 times the maximum human dose; no adequate human studies; use in pregnancy only if clearly needed.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Extent of excretion in human milk unknown; excreted in rat milk; avoid administration to nursing women if clinically possible.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Buspirone: Mechanism unknown; high affinity for serotonin 5-HT1A receptors and moderate affinity for brain D2 dopamine receptors; no significant benzodiazepine-receptor affinity.