سعر سيترونوميت 8مجم 4 اقراص ذائبة بالفم 2024

Setronomet 8 mg is an Egyptian ondansetron orally disintegrating tablet (4 tablets per pack) by Averroes Pharma, a 5-HT3 antagonist antiemetic.

• Prevention of nausea and vomiting associated with highly and moderately emetogenic cancer chemotherapyPopulation: Adults and paediatric patients (age limits per indication)DailyMed (U.S. National Library of Medicine)
• Prevention of nausea and vomiting associated with radiotherapy (total body irradiation, single high-dose or daily fractions to the abdomen)Population: Adults and paediatric patients (age limits per indication)DailyMed (U.S. National Library of Medicine)
• Prevention of postoperative nausea and/or vomitingPopulation: Adults and paediatric patients (age limits per indication)DailyMed (U.S. National Library of Medicine)

• Most common: headache, malaise/fatigue, constipation and diarrhoea (chemotherapy); headache, constipation and diarrhoea (radiotherapy); headache and hypoxia (postoperative).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity (e.g. anaphylaxis) to ondansetron or any component; concomitant apomorphine (profound hypotension and loss of consciousness).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Hypersensitivity reactions including anaphylaxis and bronchospasm; QT prolongation and torsade de pointes (avoid in congenital long QT syndrome, ECG monitoring with electrolyte abnormalities, heart failure, bradyarrhythmias or other QT-prolonging drugs); serotonin syndrome with serotonergic drugs; myocardial ischaemia; may mask progressive ileus or gastric distension.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• ApomorphineContraindicated: profound hypotension and loss of consciousness.DailyMed (U.S. National Library of Medicine)
• Serotonergic drugs (SSRIs, SNRIs and others)Risk of serotonin syndrome; monitor and discontinue ondansetron if symptoms occur.DailyMed (U.S. National Library of Medicine)
• Potent CYP3A4 inducers (phenytoin, carbamazepine, rifampicin)Increase ondansetron clearance and lower its blood levels; no dose adjustment is recommended on available data.DailyMed (U.S. National Library of Medicine)

• Published epidemiological studies on ondansetron and major birth defects are inconsistent and have methodological limitations precluding conclusions; animal studies at high multiples of the human dose showed no fetal harm.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Ondansetron: Blocks serotonin 5-HT3 receptors on vagal afferents in the gut and in the chemoreceptor trigger zone, suppressing the vomiting reflex.