سعر سيفيلام 800مجم 15 قرص 2022

Sevelam 800 mg is an Egyptian sevelamer film-coated tablet (15 tablets per pack) by Global Napi Pharmaceuticals, a non-absorbed phosphate binder.

• Control of serum phosphorus in adults and children 6 years and older with chronic kidney disease on dialysisPopulation: Adults and children ≥6 years on dialysisDailyMed (U.S. National Library of Medicine)

• In long-term studies with sevelamer hydrochloride (same active moiety): vomiting 22%, nausea 20%, diarrhoea 19%, dyspepsia 16%, abdominal pain 9%, flatulence 8% and constipation 8%.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Bowel obstruction; known hypersensitivity to sevelamer carbonate, sevelamer hydrochloride or any excipient.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Serious cases of dysphagia and oesophageal tablet retention, bowel obstruction, bleeding gastrointestinal ulcers, colitis, ulceration, necrosis and perforation have been reported with sevelamer; re-evaluate treatment if severe GI symptoms develop; consider the suspension in swallowing disorders.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Oral drugs with narrow therapeutic range where reduced absorption matters (e.g. ciclosporin, tacrolimus, levothyroxine)Sevelamer may reduce their bioavailability; separate administration times and monitor clinical response or blood levels.DailyMed (U.S. National Library of Medicine)
• Ciprofloxacin and mycophenolate mofetilExposure is reduced by sevelamer; dose separately according to the label.DailyMed (U.S. National Library of Medicine)

• Sevelamer is not absorbed systemically and maternal use is not expected to result in fetal exposure; it may lower fat-soluble vitamin and folic acid levels, so supplementation should be considered.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Not absorbed by the mother, so breastfeeding is not expected to expose the infant.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Sevelamer: Non-absorbed cationic polymer that binds dietary phosphate in the gut, reducing its absorption and lowering serum phosphorus.