سعر سبكتراسيف 1 جم حقن عضل/وريد فيال 2024

Cefepime 1 g vial for intramuscular or intravenous injection, single vial; MUP, Egypt.

• PneumoniaDailyMed (U.S. National Library of Medicine)
• Empiric therapy for febrile neutropenic patientsDailyMed (U.S. National Library of Medicine)
• Uncomplicated and complicated urinary tract infections including pyelonephritisDailyMed (U.S. National Library of Medicine)

• Most common (>=1%): local reactions, positive Coombs' test, decreased phosphorus, increased ALT/AST, prolonged PT/PTT, rash.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Immediate hypersensitivity to cefepime, other cephalosporins, penicillins or other beta-lactam antibacterials.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Hypersensitivity: cross-reactivity among beta-lactams may occur in up to 10% of penicillin-allergic patients; stop if an allergic reaction occurs.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Neurotoxicity (encephalopathy, aphasia, myoclonus, seizures, non-convulsive status epilepticus), especially with renal impairment and unadjusted doses; stop if it occurs.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Clostridioides difficile-associated diarrhoea: evaluate if diarrhoea occurs.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• No cefepime pregnancy exposures reported; decades of cephalosporin data have not established drug-associated risks of major birth defects, miscarriage or adverse outcomes; no adverse developmental effects in animal studies.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Present in human milk at low concentrations (about 0.5 mcg/mL after 1 g IV); no information on effects on the breastfed infant or milk production.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Cefepime: Bactericidal; binds penicillin-binding proteins and inhibits bacterial cell-wall synthesis (DrugBank/US labels).