سعر تورسامولكس Torsamolex‏ 10مجم 20 قرص 2026

Torsemide 10 mg tablets, pack of 20, by Marcyrl (Egypt); loop diuretic.

• Excessive urination was the most notable adverse reaction in US placebo-controlled hypertension trials (dose related: 4% at 5 mg, 15% at 10 mg vs 1% placebo).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to torsemide; anuria; hepatic coma.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Excessive diuresis may cause dehydration, hypotension and worsening renal function, including acute renal failure, especially in salt-depleted patients or those on renin-angiotensin-aldosterone inhibitors.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• May cause hypokalemia, hyponatremia, hypomagnesemia, hypocalcemia, hypochloremic alkalosis, hyperglycemia and hyperuricemia (rarely gout).International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Ototoxicity (tinnitus, usually reversible hearing loss) has been observed with loop diuretics; risk increases with high doses, severe renal impairment and hypoproteinemia.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• NSAIDs / high-dose salicylatesNSAIDs may reduce the diuretic/antihypertensive effect and have been associated with acute renal failure; high-dose salicylates may reach toxic levels because of competition for renal tubular secretion.DailyMed (U.S. National Library of Medicine)
• CYP2C9 inhibitors and inducersCYP2C9 inhibitors (e.g., amiodarone, fluconazole) increase and inducers (e.g., rifampin) decrease torsemide levels; torsemide may affect CYP2C9 substrates such as warfarin, phenytoin, celecoxib.DailyMed (U.S. National Library of Medicine)
• LithiumReduced renal clearance of lithium with high risk of lithium toxicity; monitor lithium levels.DailyMed (U.S. National Library of Medicine)

• No available data in pregnant women on major birth defects or miscarriage; no fetotoxicity or teratogenicity in rats and rabbits at moderate multiples of the human dose, but maternal/fetal toxicity at higher multiples.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• No data on presence in human milk or effects on the breastfed child; diuretics can suppress lactation.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Torsemide: Inhibits the Na-K-2Cl cotransporter in the thick ascending limb of the loop of Henle, increasing excretion of sodium, chloride and water.