سعر ALDACTAZIDE 20 TAB 2026

Aldactazide, 20 tablets of spironolactone + hydrochlorothiazide (Searle, packed/marketed by Kahira in Egypt); combined thiazide and potassium-sparing diuretic.

• Hydrochlorothiazide: weakness, orthostatic hypotension, pancreatitis, cholestatic jaundice, GI upset, acute myopia/angle-closure glaucoma, blood dyscrasias, hypersensitivity reactions. Spironolactone: gynaecomastia, GI effects, electrolyte disturbances.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Anuria, acute renal insufficiency, significant renal impairment, hypercalcaemia, hyperkalaemia, Addison's disease, allergy to thiazides or sulfonamide-derived drugs; possibly acute or severe hepatic failure.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Do not ordinarily give potassium supplements or potassium-rich diet; severe hyperkalaemia with other potassium-sparing diuretics, ACE inhibitors, ARBs, aldosterone blockers, NSAIDs, heparin. Non-melanoma skin cancer risk with hydrochlorothiazide: sun protection and skin screening.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• ACE inhibitors, ARBs, aldosterone blockers, potassium supplements, heparin/LMWHConcomitant use may lead to severe hyperkalaemia.DailyMed (U.S. National Library of Medicine)

• Hydrochlorothiazide animal studies showed no fetal harm, but there are no adequate controlled studies in pregnant women (older-format US label).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Canrenone (spironolactone metabolite) and thiazides appear in breast milk; use during breastfeeding is not recommended; if used, keep doses as low as possible.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Spironolactone:
• Hydrochlorothiazide: Promotes renal excretion of sodium and chloride, reducing intravascular volume.