سعر ALDACTONE 25MG 20 TAB 2026

Aldactone 25 mg, 20 tablets of spironolactone (Searle, packed/marketed by Kahira in Egypt); potassium-sparing diuretic.

• Gastrointestinal bleeding, ulceration, gastritis, diarrhoea, nausea, vomiting; decreased libido, erectile dysfunction, menstrual irregularities, breast pain; gynaecomastia; hyperkalaemia and electrolyte disturbances.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Hyperkalaemia; Addison's disease; concomitant use of eplerenone.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Hyperkalaemia (risk higher with renal impairment, potassium supplements, ACE inhibitors/ARBs); hypotension and worsening renal function; electrolyte and metabolic abnormalities; gynaecomastia.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Potassium supplements, ACE inhibitors, ARBs and other potassium-raising drugsConcomitant use may cause severe hyperkalaemia.DailyMed (U.S. National Library of Medicine)
• LithiumIncreased risk of lithium toxicity.DailyMed (U.S. National Library of Medicine)
• NSAIDsMay reduce the diuretic, natriuretic and antihypertensive effect.DailyMed (U.S. National Library of Medicine)

• May affect sex differentiation of the male fetus (anti-androgenic; animal data); limited human data show no association with major malformations. Avoid in pregnancy or advise of the potential risk to a male fetus.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Spironolactone not detected in breast milk; the active metabolite canrenone is present in low amounts expected to be clinically inconsequential; long-term infant effects unknown.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Spironolactone: Competitive aldosterone antagonist at the distal tubule sodium-potassium exchange site; increases sodium and water excretion while retaining potassium (US Aldactone label).