سعر ترينوفيوم Trinovume‏ 750مجم 10 اقراص 2026

Levetiracetam 750 mg film-coated tablets, pack of 10; antiepileptic (Trinovume, Sigma; manufactured by Hochster Pharmaceutical Industries, Egypt).

• Most common adverse reactions in adults: somnolence, asthenia, infection and dizziness.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Most common adverse reactions in children: fatigue, aggression, nasal congestion, decreased appetite and irritability.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Hypersensitivity to levetiracetam; anaphylaxis and angioedema have occurred.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Behavioural abnormalities and psychotic symptoms, suicidal behaviour and ideation, somnolence and fatigue, coordination difficulties, serious dermatological reactions (SJS/TEN) and DRESS/multiorgan hypersensitivity; discontinue at the first sign of rash unless clearly not drug-related.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Withdraw gradually to reduce the risk of increased seizure frequency and status epilepticus; patients should not drive or operate machinery until they know how the medicine affects them.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Prolonged experience in pregnant women has not identified a drug-associated risk of major birth defects or miscarriage; animal studies showed developmental toxicity; a pregnancy exposure registry exists.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Levetiracetam is excreted in human milk; there are no data on effects on the breastfed infant or on milk production; weigh the benefits of breastfeeding against the mother's clinical need.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Levetiracetam: The precise mechanism of the antiepileptic effect is unknown; levetiracetam binds the synaptic vesicle protein SV2A, which is thought to be involved in regulating vesicle exocytosis, and binding affinity correlated with antiseizure potency in animal models.