سعر انسياتم Unsiatem‏ 120مجم 30 قرص 2026

Febuxostat 120 mg tablets.

• Most common: liver function abnormalities, nausea, arthralgia and rash.International label, equivalent formulation · DailyMed (NLM)

• Contraindicated in patients treated with azathioprine or mercaptopurine.International label, equivalent formulation · DailyMed (NLM)

• Boxed warning: gout patients with established cardiovascular disease treated with febuxostat had a higher rate of CV death than those on allopurinol; reserve for patients with inadequate response/intolerance to allopurinol.International label, equivalent formulation · DailyMed (NLM)
• Gout flares after initiation (use NSAID or colchicine prophylaxis up to 6 months); cardiovascular death; hepatic effects (check liver tests before starting); serious skin and hypersensitivity reactions (SJS, DRESS, TEN) - stop if suspected.International label, equivalent formulation · DailyMed (NLM)

• Azathioprine, mercaptopurineContraindicated: xanthine oxidase inhibition raises their plasma levels and toxicity.DailyMed (NLM)
• TheophyllineUse with caution; xanthine oxidase inhibition may increase theophylline levels.DailyMed (NLM)

• Limited available data in pregnant women are insufficient to inform a drug-associated risk.International label, equivalent formulation · DailyMed (NLM)
• No human data on presence in milk; febuxostat is present in rat milk. Weigh benefits against risks.International label, equivalent formulation · DailyMed (NLM)

• Febuxostat: 2-arylthiazole derivative that lowers serum uric acid by potent, selective, non-purine inhibition of xanthine oxidase (oxidised and reduced forms), which catalyses hypoxanthine to xanthine to uric acid (EU SmPC).