سعر ALDOMET 500 MG 20 TAB 2026

Aldomet 500 mg, 20 tablets of methyldopa (Kahira, Egypt); centrally acting antihypertensive.

• Sedation (usually transient), headache, weakness; orthostatic hypotension, bradycardia, oedema/weight gain; dry mouth, GI upset; hyperprolactinaemia; others.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Active hepatic disease (acute hepatitis, active cirrhosis); liver disorders previously associated with methyldopa; hypersensitivity; therapy with MAO inhibitors.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Positive direct Coombs test develops in 10-20% on prolonged therapy; rare haemolytic anaemia and liver disorders can be fatal if not recognised.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Other antihypertensivesPotentiation of the antihypertensive effect.DailyMed (U.S. National Library of Medicine)
• LithiumMonitor for lithium toxicity.DailyMed (U.S. National Library of Medicine)
• Ferrous sulfate / ferrous gluconateDecreased methyldopa bioavailability, may worsen blood-pressure control.DailyMed (U.S. National Library of Medicine)

• Animal studies showed no fetal harm; no adequate controlled first-trimester studies. Use only if clearly needed; published reports across all trimesters suggest fetal harm appears remote.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Methyldopa appears in breast milk; use caution in nursing women.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Methyldopa: Metabolised to alpha-methylnorepinephrine, which probably lowers arterial pressure by stimulating central inhibitory alpha-adrenergic receptors (US label).