سعر اميلو amilo‏ 5مجم 30 قرص 2026

Amlodipine 5 mg tablets, pack of 30 (Alfacure Pharmaceuticals).

• Dose-related oedema (10.8% at 10 mg vs 0.6% placebo); dizziness, flushing and palpitation; also fatigue, nausea, abdominal pain and somnolence.International label, same formulation · DailyMed (NLM)

• Known sensitivity to amlodipine.International label, same formulation · DailyMed (NLM)

• Symptomatic hypotension is possible, particularly in severe aortic stenosis; worsening angina and acute myocardial infarction can develop after starting or increasing the dose, particularly in severe obstructive CAD; titrate slowly in severe hepatic impairment.International label, same formulation · DailyMed (NLM)

• Strong or moderate CYP3A inhibitors (e.g. itraconazole, clarithromycin, diltiazem)Increase amlodipine exposure (diltiazem +60% in elderly); monitor for hypotension and oedema.DailyMed (NLM)
• SimvastatinAmlodipine increases simvastatin exposure; limit simvastatin to 20 mg daily.DailyMed (NLM)
• Cyclosporine, tacrolimusAmlodipine may increase their exposure; monitor trough levels and adjust dose.DailyMed (NLM)

• Limited post-marketing data are not sufficient to inform a drug-associated risk for major birth defects and miscarriage; poorly controlled hypertension in pregnancy carries maternal and fetal risks; no adverse developmental effects in rats and rabbits during organogenesis.International label, same formulation · DailyMed (NLM)
• Amlodipine is present in human milk at an estimated median relative infant dose of 4.2%; no adverse effects on breastfed infants observed; no information on milk production.International label, same formulation · DailyMed (NLM)

• Amlodipine: Inhibits transmembrane calcium influx into vascular smooth muscle and cardiac muscle; peripheral arterial vasodilator.