سعر كورونافين 5 مجم 10 قرص 2022

Coronavine 5 mg tablets ×10: amlodipine (Pharopharma).

• Indicated for hypertension (to lower BP) and for coronary artery disease including chronic stable angina, vasospastic angina, and angiographically documented CAD without HF or EF <40% (US NORVASC label).Population: Adults (pediatric HTN 6–17 y per US label)DailyMed (U.S. National Library of Medicine)

• Most common adverse reaction: dose-related edema; also fatigue, nausea, abdominal pain, somnolence; flushing, dizziness, palpitation (US NORVASC label).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Contraindicated in known sensitivity to amlodipine (US NORVASC label).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Symptomatic hypotension possible (esp. severe aortic stenosis); worsening angina/MI can develop after starting or increasing dose in severe obstructive CAD; titrate slowly in severe hepatic impairment (US NORVASC label).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• SimvastatinModerateLimit simvastatin to 20 mg daily when coadministered with amlodipine (increased simvastatin exposure) (US NORVASC label).DailyMed (U.S. National Library of Medicine)

• Limited human data insufficient to inform drug-associated risk; poorly controlled hypertension in pregnancy carries maternal/fetal risks (US NORVASC PLLR).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Amlodipine is present in human milk (estimated median relative infant dose ~4.2%); no adverse effects observed on breastfed infants in limited data (US NORVASC label).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Amlodipine: Inhibits transmembrane calcium influx into vascular smooth muscle; peripheral arterial vasodilator.