سعر املوزابريل 10/20 مجم 10 كبسولات 2022

Fixed-dose combination capsule (Medizen) containing amlodipine 10 mg and benazepril 20 mg; 10 capsules.

• Hypertension in patients not adequately controlled on monotherapy with either agent.Population: AdultsDailyMed (U.S. National Library of Medicine)

• History of angioedema, with or without previous ACE inhibitor treatment; hypersensitivity to benazepril, other ACE inhibitors or amlodipine.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Co-administration with aliskiren in patients with diabetes; use within 36 hours of switching to or from a neprilysin inhibitor (e.g., sacubitril).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Fetal toxicity (boxed warning): discontinue as soon as possible when pregnancy is detected; drugs acting on the renin-angiotensin system can cause injury and death to the developing fetus.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Angioedema (including intestinal angioedema), symptomatic hypotension, hyperkalaemia, and possible worsening angina or myocardial infarction.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Potassium supplements, potassium-sparing diuretics, potassium-containing salt substitutesIncreased risk of hyperkalaemia; monitor serum potassium.DailyMed (U.S. National Library of Medicine)
• LithiumIncreased serum lithium and lithium toxicity; monitor lithium levels.DailyMed (U.S. National Library of Medicine)
• NSAIDs including COX-2 inhibitorsMay reduce antihypertensive effect and worsen renal function, particularly in elderly, volume-depleted or renally impaired patients.DailyMed (U.S. National Library of Medicine)

• Can cause fetal harm; discontinue as soon as possible when pregnancy is detected.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Minimal benazepril (less than 0.1% of the maternal dose) and amlodipine (relative infant dose about 4.2%) pass into breast milk.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Amlodipine: Inhibits transmembrane calcium influx into vascular smooth muscle and cardiac muscle; peripheral arterial vasodilator.
• Benazepril: ACE inhibitor; reduces formation of angiotensin II.