سعر امثروست 125 مجم / 5 مل معلق 60 مل 2022

Cefalexin 125 mg/5 ml oral suspension in a 60 ml bottle (Amthrost, Sigma/Sabaa, Egypt), a first-generation cephalosporin antibiotic.

• Respiratory tract infections caused by susceptible Streptococcus pneumoniae and Streptococcus pyogenes.Population: Adults and childrenDailyMed (U.S. National Library of Medicine)
• Otitis media caused by susceptible S. pneumoniae, H. influenzae, Staphylococcus aureus, S. pyogenes and Moraxella catarrhalis.Population: Adults and childrenDailyMed (U.S. National Library of Medicine)
• Skin and skin structure infections caused by susceptible S. aureus and/or S. pyogenes.Population: Adults and childrenDailyMed (U.S. National Library of Medicine)

• Most frequent: diarrhoea; also nausea, vomiting, dyspepsia, abdominal pain, allergic reactions (rash, urticaria), genital and anal pruritus, dizziness, fatigue, headache and transient hepatitis/cholestatic jaundice.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to cephalexin or other members of the cephalosporin class.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Hypersensitivity reactions including anaphylaxis, SJS, TEN and DRESS; before therapy ask about previous reactions to cephalosporins, penicillins or other beta-lactams (cross-hypersensitivity may occur in up to 10% of penicillin-allergic patients). Stop and treat if an allergic reaction occurs.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Clostridioides difficile-associated diarrhoea may occur during or up to 2 months after antibacterial use; evaluate patients with diarrhoea.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Positive direct Coombs test and haemolytic anaemia have been reported; seizures may occur in patients with renal impairment when the dose is not reduced; prothrombin time may be prolonged in at-risk patients.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• MetforminCephalexin increased metformin exposure in healthy subjects; monitor and adjust metformin dose if needed.DailyMed (U.S. National Library of Medicine)
• ProbenecidInhibits renal excretion of cephalexin; co-administration is not recommended.DailyMed (U.S. National Library of Medicine)
• Urine glucose tests (Benedict's/Fehling's solution, Clinitest)False-positive reactions may occur; use enzyme-based glucose tests.DailyMed (U.S. National Library of Medicine)

• Available human data (published studies over decades) have not identified a drug-associated risk of major birth defects, miscarriage or adverse maternal/fetal outcomes.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Cephalexin is present in human milk at low levels (relative infant dose <1%); consider benefits of breastfeeding and the mother's need for therapy.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Cefalexin (cephalexin): Bactericidal; acts by inhibiting bacterial cell-wall synthesis (US label).