سعر اريبيبركس 30 مجم 30 قرص 2026

Aripiprex 30 mg film-coated tablets (aripiprazole), an atypical antipsychotic by Andalous Pharma, Egypt; pack of 30 tablets.

• SchizophreniaPopulation: Adults and adolescents 13-17 yearsDailyMed (U.S. National Library of Medicine)
• Acute manic and mixed episodes associated with bipolar I disorderPopulation: Adults and paediatric patients 10-17 yearsDailyMed (U.S. National Library of Medicine)
• Adjunctive treatment of major depressive disorderPopulation: AdultsDailyMed (U.S. National Library of Medicine)

• Most common in adults (10% or more): nausea, vomiting, constipation, headache, dizziness, akathisia, anxiety, insomnia and restlessness. In paediatric trials: somnolence, headache, vomiting, extrapyramidal disorder, fatigue, increased appetite, insomnia, nausea, nasopharyngitis and weight increase.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• History of hypersensitivity reaction to aripiprazole (reactions ranged from pruritus/urticaria to anaphylaxis).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warning: increased mortality in elderly patients with dementia-related psychosis (not approved for this use); suicidal thoughts and behaviours with antidepressants in children, adolescents and young adults - monitor closely.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Cerebrovascular adverse events including stroke in elderly dementia patients; neuroleptic malignant syndrome; tardive dyskinesia.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Metabolic changes: hyperglycaemia/diabetes, dyslipidaemia and weight gain.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Strong CYP3A4 inhibitors (e.g. itraconazole, clarithromycin) or strong CYP2D6 inhibitors (e.g. quinidine, fluoxetine, paroxetine)Increase aripiprazole exposure; give half the usual dose (a quarter if both strong CYP2D6 and CYP3A4 inhibitors, or CYP2D6 poor metabolizers taking a strong CYP3A4 inhibitor).DailyMed (U.S. National Library of Medicine)
• Strong CYP3A4 inducers (e.g. carbamazepine, rifampin)Decrease aripiprazole exposure; double the usual dose over 1-2 weeks and reduce back over 1-2 weeks when the inducer is withdrawn.DailyMed (U.S. National Library of Medicine)

• Epidemiologic data have not established a drug-associated risk of major birth defects, miscarriage or adverse maternal outcomes; there are risks from untreated illness. Exposure may decrease post-partum milk supply. Animal studies at 10-19 times the MRHD showed developmental toxicity. A US pregnancy registry exists.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Aripiprazole is present in human milk and may cause clinically relevant, possibly reversible decreases in milk supply; monitor the breastfed infant for dehydration and poor weight gain.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Aripiprazole: Mechanism in schizophrenia and bipolar I disorder is not fully known; efficacy may be mediated by partial agonism at dopamine D2 and serotonin 5-HT1A receptors combined with antagonism at 5-HT2A receptors.