سعر افيروبريج 100 مجم / 5 مل شراب 60 مل 2022

Pregabalin 100 mg/5 ml syrup (oral solution), 60 ml bottle; gabapentinoid for neuropathic pain and partial seizures (Averroes Pharma, Egypt).

• Neuropathic pain associated with diabetic peripheral neuropathyPopulation: AdultsDailyMed (U.S. National Library of Medicine)
• Postherpetic neuralgiaPopulation: AdultsDailyMed (U.S. National Library of Medicine)
• Adjunctive therapy for partial-onset seizuresPopulation: Patients 1 month of age and olderDailyMed (U.S. National Library of Medicine)

• Most common in adults: dizziness, somnolence, dry mouth, edema, blurred vision, weight gain and abnormal thinking (mainly difficulty with concentration/attention). Pediatric epilepsy studies: somnolence, weight gain and increased appetite.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to pregabalin or any of its components.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Angioedema (face, mouth, neck; may be life-threatening) and hypersensitivity reactions: discontinue immediately; caution with prior angioedema or with ACE inhibitors.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Antiepileptic drugs increase the risk of suicidal thoughts or behavior; monitor for depression, suicidality and unusual behavior changes.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Serious, life-threatening or fatal respiratory depression may occur, especially with opioids or other CNS depressants, in underlying respiratory impairment and in the elderly; start at the lowest dose and monitor.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Opioids, benzodiazepines, alcohol and other CNS depressantsAdditive CNS and respiratory depression, which may be life-threatening; start at the lowest dose and monitor.DailyMed (U.S. National Library of Medicine)
• Thiazolidinediones (pioglitazone, rosiglitazone)Additive weight gain and peripheral edema; use with caution.DailyMed (U.S. National Library of Medicine)
• ACE inhibitorsPossible increased risk of angioedema.DailyMed (U.S. National Library of Medicine)

• Observational studies suggest a possible small increase in the overall rate of major birth defects without a consistent pattern; data on miscarriage and other outcomes are insufficient. A pregnancy exposure registry (NAAED) exists.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Pregabalin passes into breast milk (about 76% of maternal plasma concentrations; infant dose about 7% of the maternal mg/kg dose). Because of a potential tumorigenicity risk, breastfeeding is not recommended during treatment.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Pregabalin: Binds with high affinity to the alpha2-delta auxiliary subunit of voltage-gated calcium channels in CNS tissue; does not bind GABA-A/GABA-B or benzodiazepine receptors (US label).