سعر بريستافلام 100 مجم 2025

Bristaflam 100 mg film-coated tablets ×20 (SmithKline Beecham). Oral aceclofenac NSAID for pain and inflammation in OA/RA/AS (per same-formulation UK Preservex).

• Relief of pain and inflammation in osteoarthritis, rheumatoid arthritis and ankylosing spondylitis.Population: AdultsMHRA / eMC

• Common: dyspepsia, abdominal pain, nausea, diarrhoea, dizziness, elevated hepatic enzymes. Serious: GI bleed/ulcer, CV events, hypersensitivity, SJS/TEN (rare).International label, same formulation · MHRA / eMC

• Hypersensitivity to aceclofenac or excipients; NSAID hypersensitivity (asthma, rhinitis, angioedema, urticaria) to aspirin/ibuprofen/other NSAIDs.International label, same formulation · MHRA / eMC
• Active or recurrent peptic ulcer/haemorrhage; history of GI bleeding/perforation related to NSAIDs; active bleeding disorders.International label, same formulation · MHRA / eMC
• Hepatic failure; renal failure; established CHF NYHA II–IV, IHD, PAD and/or cerebrovascular disease.International label, same formulation · MHRA / eMC

• GI bleeding/ulceration/perforation can occur without warning; highest risk with history of ulcer, elderly, high dose, concomitant corticosteroids/anticoagulants/SSRIs/antiplatelets.International label, same formulation · MHRA / eMC
• Cardiovascular thrombotic risk (MI/stroke) associated with aceclofenac/diclofenac class — use lowest dose/shortest duration; caution in hypertension/heart failure.International label, same formulation · MHRA / eMC
• Monitor renal/hepatic function and blood counts on long-term use; discontinue if serious skin reactions (SJS/TEN) or liver injury signs.International label, same formulation · MHRA / eMC

• Other NSAIDs / COX-2 inhibitors / aspirinMajorAvoid combination — increased GI/adverse risk.MHRA / eMC
• Anticoagulants (e.g. warfarin)MajorNSAIDs may enhance anticoagulant effect; close monitoring.MHRA / eMC
• SSRIs / antiplatelet agents / corticosteroidsMajorIncreased GI bleeding risk.MHRA / eMC

• Avoid in pregnancy unless clearly necessary; contraindicated in third trimester. From week 20: risk of oligohydramnios and ductus arteriosus constriction — monitor if used for several days.International label, same formulation · MHRA / eMC
• Avoid in lactation unless potential benefits outweigh risks; human milk transfer not well established.International label, same formulation · MHRA / eMC

• Aceclofenac: Potent COX inhibitor reducing prostaglandin synthesis; anti-inflammatory and analgesic.