سعر كاربوسين 150 مجم فيال 2022

Egyptian carboplatin IV vial listing: Carbosin 150mg vial.

• Initial treatment of advanced ovarian carcinoma in established combination with other approved chemotherapeutic agents (e.g. with cyclophosphamide).Population: AdultsDailyMed / FDA USPI
• Palliative treatment of ovarian carcinoma recurrent after prior chemotherapy, including prior cisplatin.Population: AdultsDailyMed / FDA USPI

• Dose-limiting myelosuppression; nausea/vomiting; electrolyte losses; less often neuropathy, ototoxicity, hypersensitivity, injection-site reactions.International label, same formulation · DailyMed / FDA USPI

• History of severe allergic reactions to cisplatin or other platinum compounds; severe bone marrow depression or significant bleeding.International label, same formulation · DailyMed / FDA USPI

• BOXED WARNING: use under experienced oncology supervision; dose-related myelosuppression may be severe; cumulative anemia; frequent vomiting; anaphylactic-like reactions may occur within minutes.International label, same formulation · DailyMed / FDA USPI
• May cause fetal harm (embryotoxic/teratogenic in rats). Avoid pregnancy; discontinue breastfeeding during treatment.International label, same formulation · DailyMed / FDA USPI

• Aminoglycosides / nephrotoxic or ototoxic agentsMajorConcomitant nephrotoxic compounds may potentiate renal/audiologic toxicity.DailyMed / FDA USPI
• Phenytoin / fosphenytoinModerateDecreased phenytoin levels observed with concurrent carboplatin.DailyMed / FDA USPI

• May cause fetal harm; embryotoxic/teratogenic in rats. Advise of hazard; avoid pregnancy.International label, same formulation · DailyMed / FDA USPI
• Unknown if excreted in milk; discontinue breastfeeding during carboplatin treatment.International label, same formulation · DailyMed / FDA USPI

• Carboplatin: Produces predominantly interstrand DNA cross-links (cell-cycle nonspecific); aquation yields the active platinum species (Hospira USPI).