سعر سيسبلاتين ايبوي Cisplatin-Ebewe‏ 25مجم فيال 0.5 مجم/مل 2026

Cisplatin-Ebewe 25 mg/50 ml vial: cisplatin 0.5 mg/ml concentrate for IV infusion, 25 mg in 50 ml, marketed in Egypt by Pfizer Scientific Office (Hospira (UK)).

• Pre-existing renal impairment; myelosuppression; hearing impairment; history of allergy to cisplatin or other platinum compounds.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Cumulative nephrotoxicity, potentiated by aminoglycosides; should not be given more often than every 3-4 weeks at recommended dosage.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Aminoglycoside antibioticsPotentiate cisplatin cumulative nephrotoxicity.DailyMed (U.S. National Library of Medicine)

• US label (older format) assigns historical pregnancy Category D (see warnings: can cause fetal harm).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Cisplatin has been reported in human milk; patients receiving cisplatin should not breastfeed.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Cisplatin: Forms intra-strand DNA cross-links (primarily guanine N7), inhibiting DNA replication and transcription, leading to apoptosis of susceptible tumour cells.