سعر سيسبلاتين ميلان Cisplatine Mylan‏ 25مجم/25مل فيال 1 مجم/مل 2026

Cisplatine Mylan 25 mg/25 ml vial: cisplatin 1 mg/ml concentrate for IV infusion, 25 mg in 25 ml, marketed in Egypt by Ramco (Mylan S.A.S. (France)).

• Pre-existing renal impairment; myelosuppression; hearing impairment; history of allergy to cisplatin or other platinum compounds.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Cumulative nephrotoxicity, potentiated by aminoglycosides; should not be given more often than every 3-4 weeks at recommended dosage.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Aminoglycoside antibioticsPotentiate cisplatin cumulative nephrotoxicity.DailyMed (U.S. National Library of Medicine)

• US label (older format) assigns historical pregnancy Category D (see warnings: can cause fetal harm).International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Cisplatin has been reported in human milk; patients receiving cisplatin should not breastfeed.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Cisplatin: Forms intra-strand DNA cross-links (primarily guanine N7), inhibiting DNA replication and transcription, leading to apoptosis of susceptible tumour cells.