سعر كلافوسيجما 250 مجم/62.5 مجم معلق 60 مل 250 مجم/62.5 مجم per 5 مل 2023

Clavosigma (Sigma Tec): amoxicillin/clavulanic acid 250 mg/62.5 mg per 5 ml (stated as 250mg/62.5mg), Powder for oral suspension, Bottle 60 ml.

• Lower respiratory tract infections caused by beta-lactamase-producing H. influenzae and M. catarrhalis.DailyMed / USAntibiotics
• Acute bacterial otitis media caused by beta-lactamase-producing H. influenzae and M. catarrhalis.DailyMed / USAntibiotics
• Sinusitis caused by beta-lactamase-producing H. influenzae and M. catarrhalis.DailyMed / USAntibiotics

• Common: diarrhoea, nausea, vomiting, mucocutaneous candidiasis, rash. Less common: hepatitis/cholestatic jaundice, colitis, interstitial nephritis, haematologic effects.International label, equivalent formulation · DailyMed / USAntibiotics

• History of serious hypersensitivity (e.g. anaphylaxis or Stevens-Johnson syndrome) to amoxicillin, clavulanate or other beta-lactams.International label, equivalent formulation · DailyMed / USAntibiotics
• History of cholestatic jaundice/hepatic dysfunction associated with amoxicillin-clavulanate.International label, equivalent formulation · DailyMed / USAntibiotics

• Serious and occasionally fatal hypersensitivity reactions; severe cutaneous adverse reactions; hepatic dysfunction; Clostridioides difficile-associated diarrhoea; skin rash in mononucleosis; overgrowth of non-susceptible organisms.International label, equivalent formulation · DailyMed / USAntibiotics
• Not for viral infections; use only for susceptible bacterial infections. Complete the full prescribed course.International label, equivalent formulation · DailyMed / USAntibiotics

• ProbenecidModerateProbenecid decreases renal tubular secretion of amoxicillin and may increase and prolong blood levels.DailyMed / USAntibiotics
• Oral anticoagulantsModerateMay prolong prothrombin time; monitor INR when co-administered.DailyMed / USAntibiotics
• AllopurinolMinorConcomitant allopurinol may increase incidence of rashes.DailyMed / USAntibiotics

• Use during pregnancy only if clearly needed; reproduction studies have not shown evidence of harm; limited human data.International label, equivalent formulation · DailyMed / USAntibiotics
• Amoxicillin is excreted in human milk in small amounts; caution in nursing women (possible sensitisation/diarrhoea/candidiasis in the infant).International label, equivalent formulation · DailyMed / USAntibiotics

• Amoxicillin: Bactericidal beta-lactam that inhibits bacterial cell-wall biosynthesis during active multiplication; inactivated by beta-lactamases (US label, section 12.4).
• Clavulanic acid: Beta-lactam that inactivates some beta-lactamases, protecting amoxicillin from degradation.