سعر كورتيمنت إم إم إكس 9 مجم 30 قرص ممتد المفعول 2022

Cortiment MMX 9 mg prolonged-release tablets, 30 tablets: budesonide (Ferring/Cosmo).

• Induction of remission in adults with mild to moderate active ulcerative colitis where 5-ASA treatment is not sufficient.Population: AdultsUK electronic Medicines Compendium (eMC) / MHRA SmPC
• Induction of remission in adults with active microscopic colitis.Population: AdultsUK electronic Medicines Compendium (eMC) / MHRA SmPC

• Common: insomnia, headache, nausea, abdominal pain/distension, acne, myalgia, fatigue, decreased blood cortisol. Steroid class effects possible with high dose/prolonged use.International label, same product · UK electronic Medicines Compendium (eMC) / MHRA SmPC

• Hypersensitivity to budesonide, soya oil, peanut oil or any excipient.International label, same product · UK electronic Medicines Compendium (eMC) / MHRA SmPC

• Use caution with infections, hypertension, diabetes, osteoporosis, peptic ulcer, glaucoma/cataracts. Visual disturbance possible. Avoid potent CYP3A4 inhibitors and grapefruit juice. Contains lactose and soya lecithin. Not recommended in children.International label, same product · UK electronic Medicines Compendium (eMC) / MHRA SmPC

• CYP3A4 inhibitors (ketoconazole, itraconazole, HIV protease inhibitors, grapefruit juice)MajorExpected to increase systemic budesonide exposure and risk of systemic corticosteroid effects; avoid unless benefit outweighs risk.UK electronic Medicines Compendium (eMC) / MHRA SmPC

• Use during pregnancy only if potential benefit justifies potential risk to the fetus (UK SmPC).International label, same product · UK electronic Medicines Compendium (eMC) / MHRA SmPC
• Budesonide is excreted in breast milk; at therapeutic doses infant exposure is anticipated to be low — data support continued use during breastfeeding (UK SmPC).International label, same product · UK electronic Medicines Compendium (eMC) / MHRA SmPC

• Budesonide: Binds glucocorticoid receptors to suppress inflammatory gene expression; MMX formulation releases budesonide throughout the colon.