سعر امزاكول 500 مجم 10 اقراص 2026

• Treatment of mild to moderate exacerbations of ulcerative colitis.Population: Adults and children 6 years and olderelectronic medicines compendium (emc), UK
• Maintenance of remission of ulcerative colitis.Population: Adults and children 6 years and olderelectronic medicines compendium (emc), UK

• Most frequent adverse reactions in clinical trials: diarrhoea, nausea, abdominal pain, headache, vomiting and rash; hypersensitivity reactions, drug fever and blood dyscrasias may occur.International label, equivalent formulation · electronic medicines compendium (emc), UK

• Known hypersensitivity to mesalazine, salicylates or any of the excipients.International label, equivalent formulation · electronic medicines compendium (emc), UK
• Severe liver and/or renal impairment.International label, equivalent formulation · electronic medicines compendium (emc), UK

• Caution in patients allergic to sulfasalazine (risk of salicylate allergy). Severe cutaneous adverse reactions (DRESS, SJS, TEN) have been reported; stop immediately at the first signs of intolerance or severe skin reaction.International label, equivalent formulation · electronic medicines compendium (emc), UK
• Not recommended in impaired renal function; mesalazine-induced nephrotoxicity should be suspected if renal function deteriorates, and treatment stopped immediately.International label, equivalent formulation · electronic medicines compendium (emc), UK
• Caution in impaired liver function.International label, equivalent formulation · electronic medicines compendium (emc), UK

• Azathioprine, 6-mercaptopurine, thioguanineCombination shows a higher frequency of myelosuppressive effects; monitor white blood cells regularly and adjust the thiopurine dose.electronic medicines compendium (emc), UK
• WarfarinWeak evidence that mesalazine might decrease the anticoagulant effect of warfarin.electronic medicines compendium (emc), UK
• Other known nephrotoxic agents (e.g. NSAIDs)Concurrent use may increase the risk of renal reactions.electronic medicines compendium (emc), UK

• Should not be used during pregnancy unless the potential benefit outweighs the possible hazards; mesalazine crosses the placenta; limited human data show no increase in overall congenital malformations.International label, equivalent formulation · electronic medicines compendium (emc), UK
• Mesalazine is excreted in breast milk; only limited experience; if the infant develops diarrhoea, breast-feeding should be discontinued.International label, equivalent formulation · electronic medicines compendium (emc), UK

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