سعر فيكسوفينادين-سيد 120مجم 20 قرص 2022

Fexofenadine 120 mg film-coated tablets (CID), pack of 20.

• Relief of symptoms associated with seasonal allergic rhinitis.Population: Adults and children 12 years and olderElectronic Medicines Compendium (emc, medicines.org.uk)

• Common (≥1/100 to <1/10): headache, drowsiness, dizziness, nausea. Uncommon: fatigue. Not known: blurred vision.International label, same formulation · Electronic Medicines Compendium (emc, medicines.org.uk)
• Post-marketing: hypersensitivity reactions (angioedema, chest tightness, dyspnoea, flushing, systemic anaphylaxis), insomnia, nervousness, sleep disorders or nightmares, tachycardia, palpitations, diarrhoea, rash, urticaria, pruritus.International label, same formulation · Electronic Medicines Compendium (emc, medicines.org.uk)

• Hypersensitivity to the active substance or to any of the excipients.International label, same formulation · Electronic Medicines Compendium (emc, medicines.org.uk)

• Patients with a history of or ongoing cardiovascular disease should be warned that antihistamines as a class have been associated with tachycardia and palpitations.International label, same formulation · Electronic Medicines Compendium (emc, medicines.org.uk)
• As with most new medicines, data in the elderly and in renal or hepatic impairment are limited; administer with care in these groups.International label, same formulation · Electronic Medicines Compendium (emc, medicines.org.uk)
• Fexofenadine is unlikely to affect the ability to drive or use machines, but check individual response before driving or complex tasks.International label, same formulation · Electronic Medicines Compendium (emc, medicines.org.uk)

• Erythromycin, ketoconazole (P-glycoprotein inhibitors)Co-administration increased plasma fexofenadine levels 2-3 fold without effects on QTc and without increased adverse reactions.Electronic Medicines Compendium (emc, medicines.org.uk)
• ApalutamideApalutamide (a weak P-gp inducer) may decrease fexofenadine exposure (AUC reduced by about 30%).Electronic Medicines Compendium (emc, medicines.org.uk)
• Aluminium/magnesium hydroxide antacidsAntacid given 15 minutes before fexofenadine reduced bioavailability; leave about 2 hours between them.Electronic Medicines Compendium (emc, medicines.org.uk)

• No adequate data from use in pregnant women; limited animal studies do not indicate direct or indirect harmful effects. Should not be used during pregnancy unless clearly necessary.International label, same formulation · Electronic Medicines Compendium (emc, medicines.org.uk)
• No data on human milk content; terfenadine (parent compound) was found to cross into human milk. Not recommended for breastfeeding mothers.International label, same formulation · Electronic Medicines Compendium (emc, medicines.org.uk)

• Fexofenadine: Pharmacologically active metabolite of terfenadine; selective peripheral H1-receptor antagonist.