سعر فلاجيميد 20 قرص 2022

Flagimide tablets (tablets; diloxanide furoate + metronidazole), Kahira Pharmaceuticals, Egypt.

• Hypersensitivity to metronidazole or other nitroimidazole derivatives; use of disulfiram within the last 2 weeks; alcohol or propylene glycol-containing products during therapy and for at least 3 days afterwards; Cockayne syndrome.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• US boxed warning: metronidazole was carcinogenic in mice and rats; avoid unnecessary use and reserve it for its labelled indications.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Neurological reactions (encephalopathy, peripheral neuropathy, aseptic meningitis, convulsive seizures) have been reported; stop treatment if abnormal neurological signs appear. Severe hepatotoxicity/acute liver failure has occurred in patients with Cockayne syndrome. Severe cutaneous adverse reactions (SJS/TEN, DRESS, AGEP) and QT prolongation have been reported.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Alcohol / propylene glycolDisulfiram-like reaction (abdominal cramps, nausea, vomiting, headache, flushing); avoid during therapy and for at least 3 days afterwards.DailyMed (U.S. National Library of Medicine)
• DisulfiramPsychotic reactions reported; do not give metronidazole to patients who took disulfiram within the last 2 weeks.DailyMed (U.S. National Library of Medicine)
• Warfarin and other oral anticoagulantsPotentiated anticoagulant effect with prolonged prothrombin time; monitor PT/INR.DailyMed (U.S. National Library of Medicine)
• LithiumRaised serum lithium and possible lithium toxicity; monitor serum lithium and creatinine.DailyMed (U.S. National Library of Medicine)
• BusulfanIncreased busulfan plasma concentrations and risk of serious busulfan toxicity; avoid unless benefit outweighs risk, with busulfan level monitoring.DailyMed (U.S. National Library of Medicine)

• Metronidazole is present in human milk; the US label says a nursing mother may pump and discard milk during therapy and for 48 hours after the last dose.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

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