سعر فلوكسوتينازول 10 قرص 2026

Floxotinazole film-coated tablets (El Obour Modern Pharma for Advocure, Egypt): an oral fixed-dose combination of ciprofloxacin 500 mg (fluoroquinolone antibacterial) and tinidazole 600 mg (nitroimidazole antiprotozoal/anti-anaerobic) per tablet, pack of 10 tablets.

• Ciprofloxacin component: contraindicated in patients with known hypersensitivity to ciprofloxacin, any other quinolone or any product component, and with concomitant tizanidine.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Tinidazole component: contraindicated with a previous history of hypersensitivity to tinidazole or other nitroimidazole derivatives, and in patients with Cockayne syndrome.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Boxed warning (ciprofloxacin): fluoroquinolones are associated with disabling and potentially irreversible serious adverse reactions, including tendinitis and tendon rupture, peripheral neuropathy and central nervous system effects, and may exacerbate muscle weakness in myasthenia gravis. Discontinue immediately if these occur; avoid in patients with a history of myasthenia gravis.General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Ciprofloxacin may prolong the QT interval; avoid use with other drugs known to prolong the QT interval (e.g. class IA or III antiarrhythmics, tricyclic antidepressants, macrolides, antipsychotics).General active-ingredient information · DailyMed (U.S. National Library of Medicine)
• Boxed warning (tinidazole): carcinogenicity has been seen in mice and rats treated chronically with metronidazole, a structurally related nitroimidazole; use should be limited to approved indications.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• TizanidineConcomitant use with ciprofloxacin is contraindicated because ciprofloxacin potentiates the hypotensive and sedative effects of tizanidine.DailyMed (U.S. National Library of Medicine)
• TheophyllineAvoid use: ciprofloxacin increases theophylline exposure and the risk of CNS and other adverse reactions; if unavoidable, monitor theophylline levels and adjust the dose.DailyMed (U.S. National Library of Medicine)
• Alcohol (alcoholic beverages / preparations)Avoid alcohol during tinidazole therapy and for 3 days afterwards (interaction reported for the related nitroimidazole metronidazole).DailyMed (U.S. National Library of Medicine)
• Warfarin and other oral coumarin anticoagulantsTinidazole may enhance the anticoagulant effect (prolonged prothrombin time); the anticoagulant dose may need adjustment during and up to 8 days after tinidazole therapy.DailyMed (U.S. National Library of Medicine)

• Ciprofloxacin component: decades of published experience in pregnant women have not identified a drug-associated risk of major birth defects, miscarriage or adverse maternal or fetal outcomes, although the available studies have limitations.General active-ingredient information · DailyMed (U.S. National Library of Medicine)

• Ciprofloxacin: Bactericidal fluoroquinolone that inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, blocking DNA replication.
• Tinidazole: