سعر اوجمنتين 1.2 جم 1فيال 2022

Augmentin 1.2 g vial for intravenous use (amoxicillin 1000 mg + clavulanic acid 200 mg); manufactured in Egypt by Medical Union Pharmaceuticals (MUP) for GSK. Parenteral penicillin antibiotic with a beta-lactamase inhibitor.

• Upper respiratory tract infections (including ENT), e.g. recurrent tonsillitis, sinusitis, otitis mediaPopulation: Adults and childrenGlaxoSmithKline Pharmaceuticals Limited (GSK India)
• Lower respiratory tract infections, e.g. acute exacerbation of COPD/chronic bronchitis, lobar and bronchopneumoniaPopulation: Adults and childrenGlaxoSmithKline Pharmaceuticals Limited (GSK India)
• Genito-urinary tract infections, e.g. cystitis, urethritis, pyelonephritisPopulation: Adults and childrenGlaxoSmithKline Pharmaceuticals Limited (GSK India)

• Common: mucocutaneous candidiasis and diarrhoea; thrombophlebitis at the injection site is rare; hepatic events and rare severe skin reactions (e.g. Stevens-Johnson syndrome, TEN, DRESS, AGEP) have been reported.International label, same product · GlaxoSmithKline Pharmaceuticals Limited (GSK India)

• Hypersensitivity to beta-lactams (e.g. penicillins and cephalosporins).International label, same product · GlaxoSmithKline Pharmaceuticals Limited (GSK India)
• Previous history of Augmentin-associated jaundice/hepatic dysfunction.International label, same product · GlaxoSmithKline Pharmaceuticals Limited (GSK India)

• Serious and occasionally fatal hypersensitivity (anaphylactic) reactions, including progression to Kounis syndrome, and drug-induced enterocolitis syndrome have been reported; enquire about beta-lactam allergy before treatment and discontinue if an allergic reaction occurs.International label, same product · GlaxoSmithKline Pharmaceuticals Limited (GSK India)
• Haemophagocytic lymphohistiocytosis/macrophage activation syndrome has been reported; evaluate promptly and discontinue unless an alternative cause is found.International label, same product · GlaxoSmithKline Pharmaceuticals Limited (GSK India)
• Hepatic events (including cholestatic jaundice) may occur, may not appear until several weeks after treatment has ceased, and very rarely have been fatal; use with caution in hepatic impairment.International label, same product · GlaxoSmithKline Pharmaceuticals Limited (GSK India)

• ProbenecidNot recommended; increases and prolongs amoxicillin (not clavulanic acid) blood levels.GlaxoSmithKline Pharmaceuticals Limited (GSK India)
• AllopurinolMay increase the likelihood of allergic skin reactions.GlaxoSmithKline Pharmaceuticals Limited (GSK India)
• Oral anticoagulants (warfarin, acenocoumarol)Increased INR reported; monitor prothrombin time/INR and adjust the anticoagulant dose if needed.GlaxoSmithKline Pharmaceuticals Limited (GSK India)

• Use in pregnancy should be avoided, especially during the first trimester, unless considered essential by the physician; prophylactic use in preterm premature rupture of membranes may be associated with an increased risk of necrotising enterocolitis in neonates.International label, same product · GlaxoSmithKline Pharmaceuticals Limited (GSK India)
• May be administered during lactation; apart from the risk of sensitisation associated with excretion of trace quantities in breast milk, no detrimental effects are known for the breast-fed infant.International label, same product · GlaxoSmithKline Pharmaceuticals Limited (GSK India)

• Amoxicillin (as sodium): Bactericidal beta-lactam that inhibits bacterial cell-wall biosynthesis during active multiplication; inactivated by beta-lactamases (US label, section 12.4).
• Clavulanic acid (as potassium clavulanate): Beta-lactam that inactivates some beta-lactamases, protecting amoxicillin from degradation.