سعر فلوروفلوكس 400مجم 10 قرص 2024

Moxifloxacin 400 mg film-coated tablets, pack of 10, by Global Napi Pharmaceuticals for TA Pharma (Egypt); fluoroquinolone antibacterial.

• Community-acquired pneumonia caused by susceptible bacteria.Population: Adults 18 years and olderDailyMed (U.S. National Library of Medicine)
• Uncomplicated and complicated skin and skin structure infections.Population: Adults 18 years and olderDailyMed (U.S. National Library of Medicine)
• Complicated intra-abdominal infections.Population: Adults 18 years and olderDailyMed (U.S. National Library of Medicine)

• The most common adverse reactions leading to discontinuation with the 400 mg oral dose were nausea, diarrhoea, dizziness and vomiting.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• History of hypersensitivity to moxifloxacin or any other quinolone.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warning: fluoroquinolones are associated with disabling and potentially irreversible serious reactions (tendinitis and tendon rupture, peripheral neuropathy, CNS effects) and may exacerbate myasthenia gravis; stop at once if these occur and avoid in known myasthenia gravis.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Prolongs the QT interval in some patients; avoid with class IA or class III antiarrhythmics and in patients with risk factors for QT prolongation.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Blood glucose disturbances can occur; monitor glucose carefully in patients on antidiabetic agents.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Antacids, sucralfate, multivitamins and other multivalent cations (Mg, Al, Fe, Zn)Chelation decreases moxifloxacin absorption; take moxifloxacin at least 4 hours before or 8 hours after them.DailyMed (U.S. National Library of Medicine)
• WarfarinAnticoagulant effect enhanced; monitor prothrombin time/INR and bleeding.DailyMed (U.S. National Library of Medicine)
• Class IA and class III antiarrhythmicsProarrhythmic effect may be enhanced; avoid concomitant use.DailyMed (U.S. National Library of Medicine)

• No human data establish a drug-associated risk; based on animal studies moxifloxacin may cause fetal harm; advise pregnant women of the potential risk.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Unknown whether present in human milk; excreted in rat milk; weigh the benefits of breastfeeding against the mother's need and potential risks to the infant.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Moxifloxacin: Bactericidal; inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, enzymes needed for DNA replication, transcription, repair and recombination.