سعر فيوسيديك بلس كريم 15 جم 2022

Topical cream combining fusidic acid with betamethasone (strengths and ester not stated), 15 g tube, by Sigma (Egypt).

• Eczematous dermatoses (including atopic eczema, infantile eczema, discoid eczema, stasis eczema, contact eczema and seborrhoeic eczema) where secondary bacterial infection is confirmed or suspected.Population: Adults and childrenelectronic medicines compendium (eMC), UK

• Uncommon: hypersensitivity, contact dermatitis, eczema (condition aggravated), application-site burning, pruritus and pain/irritation, dry skin. Rare: erythema, urticaria, rash. Not known: blurred vision, steroid withdrawal reactions. Corticosteroid class effects include skin atrophy, telangiectasia, striae, folliculitis, hypertrichosis, perioral dermatitis, depigmentation and HPA-axis suppression.International label, equivalent formulation · electronic medicines compendium (eMC), UK

• Hypersensitivity to fusidic acid/sodium fusidate, betamethasone valerate or excipients; systemic fungal infections; primary skin infections caused by fungi, viruses or bacteria that are untreated or not controlled by appropriate treatment; skin manifestations of tuberculosis or syphilis; perioral dermatitis; rosacea.International label, equivalent formulation · electronic medicines compendium (eMC), UK

• Avoid long-term continuous treatment; systemic absorption of the corticosteroid can cause reversible HPA-axis suppression and Cushing-type effects, with children at greater risk; occlusion and large areas increase absorption.International label, equivalent formulation · electronic medicines compendium (eMC), UK
• Use with care near the eyes; topical corticosteroids may cause cataract or glaucoma, and visual disturbance should prompt ophthalmological assessment (including central serous chorioretinopathy).International label, equivalent formulation · electronic medicines compendium (eMC), UK
• Skin atrophy can occur, especially on the face; bacterial resistance to fusidic acid has been reported, so limit the course (normally 14 days or less); topical steroid withdrawal reactions may occur after long-term use.International label, equivalent formulation · electronic medicines compendium (eMC), UK

• Systemically administered medicinal productsNo interaction studies performed; interactions are considered minimal.electronic medicines compendium (eMC), UK

• Fusidic acid: systemic exposure negligible. Betamethasone valerate: limited human data and reproductive toxicity in animals; the UK product should not be used in pregnancy unless clearly necessary.International label, equivalent formulation · electronic medicines compendium (eMC), UK
• Can be used during breastfeeding but should not be applied to the breasts.International label, equivalent formulation · electronic medicines compendium (eMC), UK

• Fusidic acid: Inhibits bacterial protein synthesis by binding elongation factor G (EF-G) on the ribosome, preventing translocation; mainly active against Gram-positive bacteria such as Staphylococcus aureus.
• Betamethasone (ester not stated): Glucocorticoid receptor agonist with anti-inflammatory, antipruritic and vasoconstrictive actions in the skin.