سعر فيوتاكوكسيب 90مجم 30 قرص 2024

Etoricoxib 90 mg film-coated tablets, 30 per pack; selective COX-2 inhibitor NSAID by Future Pharmaceutical Industries (Egypt).

• Symptomatic relief of osteoarthritis, rheumatoid arthritis and ankylosing spondylitis, pain and inflammation of acute gouty arthritis, and short-term treatment of moderate pain after dental surgery, in adults and adolescents 16 years and older (UK SmPC).Population: Adults and adolescents 16 years and olderelectronic medicines compendium (eMC)

• Very common: abdominal pain; common include oedema/fluid retention, dizziness, headache, hypertension, palpitations, dyspepsia, heartburn, diarrhoea and nausea.International label, same formulation · electronic medicines compendium (eMC)

• Active peptic ulceration or GI bleeding; history of bronchospasm, rhinitis, nasal polyps, angioedema or urticaria after aspirin/NSAIDs; pregnancy and lactation; severe hepatic dysfunction; creatinine clearance <30 mL/min; children under 16; inflammatory bowel disease.International label, same formulation · electronic medicines compendium (eMC)
• Congestive heart failure (NYHA II-IV); hypertension persistently above 140/90 mmHg and not adequately controlled; established ischaemic heart disease, peripheral arterial disease and/or cerebrovascular disease.International label, same formulation · electronic medicines compendium (eMC)

• Upper GI complications (perforation, ulcers, bleeding), some fatal, especially in the elderly, with concomitant NSAIDs/aspirin or prior GI disease; COX-2 inhibitors may increase the risk of thrombotic events (myocardial infarction, stroke) with dose and duration.International label, same formulation · electronic medicines compendium (eMC)

• Warfarin and other oral anticoagulantsEtoricoxib 120 mg increased INR by about 13%; monitor INR, especially at initiation or dose change.electronic medicines compendium (eMC)
• Diuretics, ACE inhibitors and angiotensin II antagonistsNSAIDs may reduce the antihypertensive effect.electronic medicines compendium (eMC)

• No clinical data in pregnancy; animal studies showed reproductive toxicity; may cause uterine inertia and premature closure of the ductus arteriosus in the last trimester; contraindicated in pregnancy.International label, same formulation · electronic medicines compendium (eMC)
• Unknown whether excreted in human milk (excreted in rat milk); women who use etoricoxib must not breastfeed.International label, same formulation · electronic medicines compendium (eMC)

• Etoricoxib: Selective COX-2 inhibitor within the clinical dose range; no inhibition of COX-1 at doses up to 150 mg daily and no effect on platelet function.