سعر جانفورت قطرة عين 5 مل 2022

Bimatoprost + timolol fixed-combination eye drops (Allergan brand, distributed by Soficopharm), single bottle (Arabic listing: 5 ml), for lowering intraocular pressure.

• Reduction of intraocular pressure in adults with open-angle glaucoma or ocular hypertension who are insufficiently responsive to topical beta-blockers or prostaglandin analogues.Population: Adults with open-angle glaucoma or ocular hypertensionelectronic medicines compendium (eMC)

• Most adverse reactions in clinical studies were ocular and mild; the most common was conjunctival hyperaemia (about 26% of patients over 12 months; led to discontinuation in 1.5%).International label, same formulation · electronic medicines compendium (eMC)

• Hypersensitivity to the active substances or excipients.International label, same formulation · electronic medicines compendium (eMC)
• Reactive airway disease including bronchial asthma or a history of asthma; severe chronic obstructive pulmonary disease.International label, same formulation · electronic medicines compendium (eMC)
• Sinus bradycardia, sick sinus syndrome, sino-atrial block, second- or third-degree AV block not controlled with a pacemaker; overt cardiac failure; cardiogenic shock.International label, same formulation · electronic medicines compendium (eMC)

• The active substances may be absorbed systemically; because of timolol, the same cardiovascular, pulmonary and other adverse reactions as with systemic beta-blockers may occur, although less often.International label, same formulation · electronic medicines compendium (eMC)
• Patients with cardiovascular disease (e.g. coronary heart disease, Prinzmetal angina, cardiac failure) or hypotension should be critically assessed before beta-blocker therapy.International label, same formulation · electronic medicines compendium (eMC)

• Oral calcium channel blockers, guanethidine, beta-blockers, parasympathomimetics, anti-arrhythmics (incl. amiodarone), digitalis glycosidesPotential additive effects resulting in hypotension and/or marked bradycardia with ophthalmic beta-blockers.electronic medicines compendium (eMC)
• CYP2D6 inhibitors (e.g. quinidine, fluoxetine, paroxetine)Potentiated systemic beta-blockade (e.g. decreased heart rate, depression) reported with timolol.electronic medicines compendium (eMC)
• Adrenaline (epinephrine)Mydriasis occasionally reported with concomitant ophthalmic beta-blockers and adrenaline.electronic medicines compendium (eMC)

• No adequate data on the combination in pregnant women; should not be used during pregnancy unless clearly necessary. Oral beta-blockers have shown a risk of intrauterine growth retardation; neonatal beta-blockade signs (bradycardia, hypotension, respiratory distress, hypoglycaemia) have been seen when beta-blockers were given until delivery.International label, same formulation · electronic medicines compendium (eMC)
• Beta-blockers are excreted in breast milk; bimatoprost is excreted in rat milk. GANFORT should not be used by breast-feeding women.International label, same formulation · electronic medicines compendium (eMC)

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