سعر جازيك 20مجم 7 كبسولات 2023

Omeprazole 20 mg capsules (7 capsules), a proton pump inhibitor for acid-related disorders, marketed in Egypt (MUP / Acino).

• Short-term treatment of active duodenal ulcer.Population: AdultsDailyMed (U.S. National Library of Medicine)
• H. pylori eradication (with clarithromycin and amoxicillin, or with clarithromycin) to reduce the risk of duodenal ulcer recurrence.Population: AdultsDailyMed (U.S. National Library of Medicine)
• Short-term treatment (4-8 weeks) of active benign gastric ulcer.Population: AdultsDailyMed (U.S. National Library of Medicine)

• Most common (2% or more): headache, abdominal pain, nausea, diarrhea, vomiting and flatulence.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity (including anaphylaxis) to the formulation or any substituted benzimidazole.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Patients receiving rilpivirine-containing products.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Symptomatic response does not exclude gastric malignancy; consider further evaluation in adults with suboptimal response or early relapse.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Acute tubulointerstitial nephritis, Clostridioides difficile-associated diarrhea, bone fracture with high-dose long-term use, severe cutaneous adverse reactions, cutaneous and systemic lupus erythematosus, vitamin B12 deficiency, hypomagnesemia, fundic gland polyps; use the lowest dose and shortest duration appropriate.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Serum chromogranin A rises and may give false-positive neuroendocrine tumour tests; stop omeprazole at least 14 days before testing.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• ClopidogrelOmeprazole (CYP2C19 inhibition) reduces the active metabolite of clopidogrel; avoid concomitant use and consider alternative antiplatelet therapy.DailyMed (U.S. National Library of Medicine)
• Rilpivirine, atazanavir, nelfinavirDecreased antiretroviral exposure may reduce efficacy and promote resistance; rilpivirine is contraindicated.DailyMed (U.S. National Library of Medicine)
• St John's wort, rifampinCYP2C19/CYP3A4 inducers can substantially decrease omeprazole concentrations; avoid concomitant use.DailyMed (U.S. National Library of Medicine)

• No adequate studies in pregnant women; epidemiologic data do not show an increased risk of major malformations with first-trimester use; dose-dependent embryo-lethality in animals at high multiples of the human dose.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Limited data suggest omeprazole may be present in human milk; no data on effects on the breastfed infant or milk production.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Omeprazole: Suppresses gastric acid secretion by specific inhibition of the H+/K+ ATPase (proton pump) at the secretory surface of the gastric parietal cell (US Zegerid label).