سعر جينومونيكس 0.4% كريم مهبلي 30 جم 2024

Gynomonix 0.4% vaginal cream 30 gm (Medizen Pharmaceutical Industries): vaginal cream containing terconazole 0.4%; vaginal azole antifungal.

• Local treatment of vulvovaginal candidiasis (moniliasis); confirm diagnosis by KOH smear and/or culture.DailyMed (U.S. National Library of Medicine)

• In US controlled trials, the adverse reactions most likely related to terconazole 0.4% cream were headache (26% vs 17% placebo) and body pain (2.1% vs 0%); fever, chills and vulvovaginal burning, itching and irritation were also reported.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to terconazole or to any component of the product.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Anaphylaxis and toxic epidermal necrolysis have been reported during terconazole therapy; discontinue therapy if either develops.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Oral contraceptivesThe therapeutic effect of terconazole is not affected by oral contraceptive use.DailyMed (U.S. National Library of Medicine)

• Labelled under the former FDA Pregnancy Category C: no teratogenicity in rats or rabbits at oral doses well above the intravaginal human dose, but embryotoxicity (reduced litter size, fetal weight, delayed ossification) at 20-40 mg/kg in animals.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Not known whether terconazole is excreted in human milk; reduced early survival of rat pups exposed via milk at high oral doses. Decide whether to stop nursing or the drug, considering its importance to the mother.International label, same formulation · DailyMed (U.S. National Library of Medicine)

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