سعر هيروكساسين 500مجم 10 اقراص 2024

Heroxacin 500 mg ciprofloxacin scored film-coated tablets, pack of 10, marketed in Egypt by EGPI > Hero Pharm; fluoroquinolone antibacterial.

• Adults: skin and skin-structure infections, bone and joint infections, complicated intra-abdominal infections, infectious diarrhoea, typhoid fever, uncomplicated cervical/urethral gonorrhoea, chronic bacterial prostatitis, lower respiratory tract infections and urinary tract infections caused by susceptible bacteria.Population: Adults (18 years and older)DailyMed (U.S. National Library of Medicine)
• Inhalational anthrax (post-exposure) and plague in adults and pediatric patients; complicated UTI and pyelonephritis in pediatric patients 1-17 years (not first choice).Population: Adults and pediatric patientsDailyMed (U.S. National Library of Medicine)
• Acute exacerbation of chronic bronchitis, acute uncomplicated cystitis and acute sinusitis only in patients with no alternative treatment options (boxed warning).Population: AdultsDailyMed (U.S. National Library of Medicine)

• Most common (>=1%): nausea, diarrhoea, abnormal liver function tests, vomiting and rash.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to ciprofloxacin, any other quinolone or any product component.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Concomitant administration with tizanidine.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warning: disabling and potentially irreversible serious adverse reactions including tendinitis and tendon rupture, peripheral neuropathy and CNS effects; discontinue immediately if they occur. May exacerbate muscle weakness in myasthenia gravis (avoid).International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Serious hypersensitivity reactions (including anaphylaxis) - stop at the first sign of rash, jaundice or hypersensitivity; hepatotoxicity; Clostridioides difficile-associated diarrhoea; QT prolongation (avoid with known QT prolongation, hypokalaemia or other QT-prolonging drugs); aortic aneurysm and dissection; photosensitivity; musculoskeletal disorders in pediatric patients.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• TizanidinePotentiation of hypotensive and sedative effects; contraindicated.DailyMed (U.S. National Library of Medicine)
• TheophyllineIncreased risk of serious and fatal CNS and other reactions; avoid, or monitor serum levels and adjust the dose.DailyMed (U.S. National Library of Medicine)
• Drugs that prolong the QT interval (class IA/III antiarrhythmics, tricyclics, macrolides, antipsychotics)Further QT prolongation; avoid use.DailyMed (U.S. National Library of Medicine)

• Several decades of published experience in pregnancy have not identified a drug-associated risk of major birth defects, miscarriage or adverse maternal or fetal outcomes; animal studies at tested doses showed no malformations.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Ciprofloxacin is present in human milk. Because of potential serious adverse reactions (arthropathy in juvenile animals), for most indications breastfeeding is not recommended (or milk pumped and discarded) during treatment and for 2 days after the last dose; monitor the infant for loose or bloody stools and candidiasis.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Ciprofloxacin: Bactericidal fluoroquinolone that inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, blocking DNA replication.