سعر كانزار 100مجم 8 اقراص 2022

Kanzar 100 mg film-coated tablets (losartan potassium), pack of 8, Hikma Pharma, Egypt.

• Hypertension in adults and children older than 6 years, to lower blood pressure.Population: Adults and children > 6 yearsDailyMed (U.S. National Library of Medicine)
• Reduction of the risk of stroke in hypertensive patients with left ventricular hypertrophy (evidence suggests the benefit does not apply to Black patients).Population: AdultsDailyMed (U.S. National Library of Medicine)
• Diabetic nephropathy with elevated serum creatinine and proteinuria in type 2 diabetic patients with a history of hypertension.Population: AdultsDailyMed (U.S. National Library of Medicine)

• Most common adverse reactions (>= 2% and more than placebo): dizziness, upper respiratory infection, nasal congestion and back pain.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Hypersensitivity to any component of the product.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Coadministration with aliskiren in patients with diabetes.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warning (fetal toxicity): drugs acting directly on the renin-angiotensin system can cause injury and death to the developing fetus; discontinue as soon as possible when pregnancy is detected.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Hypotension: correct volume or salt depletion before starting treatment.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Monitor renal function and serum potassium in susceptible patients.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• LithiumIncreased serum lithium concentrations and risk of lithium toxicity; monitor lithium levels.DailyMed (U.S. National Library of Medicine)
• NSAIDs including selective COX-2 inhibitorsIncreased risk of renal impairment and reduced antihypertensive effect; monitor renal function.DailyMed (U.S. National Library of Medicine)
• Dual RAS blockade (ACE inhibitors, other ARBs, aliskiren)Increased risk of renal impairment, hypotension and hyperkalaemia; aliskiren is contraindicated in patients with diabetes.DailyMed (U.S. National Library of Medicine)

• Boxed warning (fetal toxicity): drugs acting directly on the renin-angiotensin system can cause injury and death to the developing fetus; discontinue as soon as possible when pregnancy is detected.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Unknown whether losartan is excreted in human milk (significant levels in rat milk); decide whether to discontinue nursing or the drug.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Losartan potassium: Losartan and its principal active metabolite selectively block binding of angiotensin II to the AT1 receptor, blocking its vasoconstrictor and aldosterone-secreting effects.