سعر لوسارتان 100 مجم 14 قرص 2022

Losartan 100mg 14 scored f.c.tab by Mepaco (Egypt): losartan potassium 100 mg film-coated tablet (scored), an angiotensin II receptor blocker for hypertension.

• Treatment of hypertension to lower blood pressure, which reduces the risk of fatal and non-fatal cardiovascular events, primarily strokes and myocardial infarctions.Population: Adults and children 6 years and olderDailyMed (U.S. National Library of Medicine)
• Reduction of the risk of stroke in patients with hypertension and left ventricular hypertrophy (evidence suggests this benefit does not apply to Black patients).Population: AdultsDailyMed (U.S. National Library of Medicine)
• Treatment of diabetic nephropathy with elevated serum creatinine and proteinuria (urinary albumin to creatinine ratio >=300 mg/g) in patients with type 2 diabetes and a history of hypertension.Population: AdultsDailyMed (U.S. National Library of Medicine)

• In hypertension trials the overall incidence of adverse events was similar to placebo; reactions reported more often than placebo include dizziness, upper respiratory infection, nasal congestion and back pain.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Hypersensitivity to any component; co-administration with aliskiren in patients with diabetes.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warning: fetal toxicity - discontinue as soon as possible when pregnancy is detected; drugs acting directly on the renin-angiotensin system can cause injury and death to the developing fetus.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• Symptomatic hypotension may occur in volume- or salt-depleted patients (correct before starting); changes in renal function including acute renal failure; hyperkalaemia.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Agents increasing serum potassium (potassium-sparing diuretics, potassium supplements, salt substitutes)Risk of hyperkalaemia; monitor serum potassium.DailyMed (U.S. National Library of Medicine)
• LithiumIncreased serum lithium concentrations and lithium toxicity reported; monitor lithium levels.DailyMed (U.S. National Library of Medicine)
• NSAIDs including COX-2 inhibitorsIn elderly, volume-depleted or renally impaired patients may deteriorate renal function (possible acute renal failure); may attenuate the antihypertensive effect; monitor renal function.DailyMed (U.S. National Library of Medicine)

• Drugs acting on the renin-angiotensin system during the second and third trimesters reduce fetal renal function and increase fetal and neonatal morbidity and death; discontinue as soon as possible when pregnancy is detected.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)
• It is not known whether losartan is excreted in human milk; significant levels of losartan and its active metabolite are present in rat milk; decide whether to discontinue nursing or the drug.International label, equivalent formulation · DailyMed (U.S. National Library of Medicine)

• Losartan potassium: Losartan and its principal active metabolite selectively block binding of angiotensin II to the AT1 receptor, blocking its vasoconstrictor and aldosterone-secreting effects; they do not inhibit ACE.