سعر كينوموكسي 400مجم 10 اقراص 2025

Kinomoxi 400 mg film-coated tablets, pack of 10 (Al Esraa Pharmaceutical Optima, Egypt): moxifloxacin, a fluoroquinolone antibacterial.

• Community-acquired pneumonia (adults)Population: Adults 18 years and olderDailyMed (U.S. National Library of Medicine)
• Uncomplicated skin and skin structure infectionsPopulation: Adults 18 years and olderDailyMed (U.S. National Library of Medicine)
• Complicated skin and skin structure infectionsPopulation: Adults 18 years and olderDailyMed (U.S. National Library of Medicine)

• Most common adverse reactions (>=3%): nausea, diarrhoea, headache and dizziness.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• History of hypersensitivity to moxifloxacin or any member of the quinolone class.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warning: fluoroquinolones are associated with disabling and potentially irreversible serious reactions including tendinitis and tendon rupture, peripheral neuropathy and CNS effects; discontinue immediately if these occur. May exacerbate muscle weakness in myasthenia gravis; avoid in patients with a history of myasthenia gravis.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Because of serious adverse reactions, reserve moxifloxacin for acute bacterial sinusitis and acute bacterial exacerbation of chronic bronchitis for patients with no alternative treatment options.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• QT prolongation and isolated torsade de pointes reported; avoid in known QT prolongation, clinically significant bradycardia, acute myocardial ischaemia, hypokalaemia, hypomagnesaemia and with other QT-prolonging drugs.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Antacids, sucralfate, multivalent cations (iron, zinc), multivitaminsChelation reduces moxifloxacin absorption; take moxifloxacin at least 4 hours before or 8 hours after these products.DailyMed (U.S. National Library of Medicine)
• WarfarinAnticoagulant effect enhanced; monitor prothrombin time/INR and bleeding.DailyMed (U.S. National Library of Medicine)
• Class IA and Class III antiarrhythmicsProarrhythmic effect may be enhanced; avoid concomitant use.DailyMed (U.S. National Library of Medicine)

• No human data establishing a drug-associated risk; animal studies at maternally toxic doses showed decreased neonatal weight, skeletal variations and increased fetal loss, so moxifloxacin may cause fetal harm. Advise pregnant women of the potential risk.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Unknown whether present in human milk; very low excretion in rat milk. Weigh breastfeeding benefits against the mother's need and potential adverse effects on the infant.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Moxifloxacin: Bactericidal; inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, enzymes needed for DNA replication, transcription, repair and recombination.