سعر كيبروكينزا 750 مجم 10 اقراص 2022

Ciprofloxacin 750 mg film-coated tablets, 10 per pack (Kiprokinza, Tabuk Pharmaceutical Manufacturing Company / Al Ansar for Marketing); fluoroquinolone antibacterial.

• Infections caused by susceptible bacteria including skin, bone and joint, intra-abdominal, lower respiratory and urinary tract infections, infectious diarrhoea, typhoid fever, gonorrhoea, prostatitis, anthrax and plague (US label).Population: Adults (selected pediatric indications)DailyMed (U.S. National Library of Medicine)

• Most frequently reported adverse reactions in clinical trials: nausea (2.5%), diarrhoea (1.6%), abnormal liver function tests (1.3%), vomiting (1%) and rash (1%).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Known hypersensitivity to ciprofloxacin, other quinolones or any product component.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Concomitant administration with tizanidine.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Boxed warning: fluoroquinolones are associated with disabling and potentially irreversible serious reactions (tendinitis and tendon rupture, peripheral neuropathy, central nervous system effects) and may exacerbate myasthenia gravis; discontinue at the first sign and avoid in patients with myasthenia gravis.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Reserve ciprofloxacin for acute uncomplicated cystitis, acute sinusitis and acute exacerbation of chronic bronchitis in patients with no alternative treatment options.International label, same formulation · DailyMed (U.S. National Library of Medicine)

• TizanidineContraindicated: ciprofloxacin markedly increases tizanidine exposure (hypotension, sedation).DailyMed (U.S. National Library of Medicine)
• TheophyllineIncreased theophylline levels with risk of serious and fatal reactions; monitor theophylline levels.DailyMed (U.S. National Library of Medicine)
• Multivalent cation products (antacids, iron, zinc, calcium), sucralfateChelation reduces ciprofloxacin absorption; separate dosing (2 hours before or 6 hours after).DailyMed (U.S. National Library of Medicine)

• Decades of experience in pregnant women have not identified a drug-associated risk of major birth defects, miscarriage or adverse maternal or fetal outcomes; animal studies showed no malformations.International label, same formulation · DailyMed (U.S. National Library of Medicine)
• Ciprofloxacin is excreted in human milk; because of the potential for serious adverse reactions, breastfeeding is not recommended during treatment and for 2 days after the last dose (or milk may be pumped and discarded).International label, same formulation · DailyMed (U.S. National Library of Medicine)

• Ciprofloxacin: Bactericidal fluoroquinolone that inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, blocking DNA replication.